back to indexUsing Failures, Movement & Balance to Learn Faster | Huberman Lab Podcast #7

            
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                 Welcome to the Huberman Lab Podcast,
             
            
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                 where we discuss science and science-based tools
             
            
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                 for everyday life.
             
            
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                 My name is Andrew Huberman,
             
            
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                 and I'm a professor of neurobiology and ophthalmology
             
            
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                 at Stanford School of Medicine.
             
            
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                 This podcast is separate
             
            
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                 from my teaching and research roles at Stanford.
             
            
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                 It is, however, part of my desire and effort
             
            
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                 to bring you zero cost to consumer information
             
            
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                 about science and science-related tools.
             
            
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                 In keeping with that theme,
             
            
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                 I'd like to thank the sponsors of today's podcast.
             
            
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                 Our first sponsor is Headspace.
             
            
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                 Headspace is a meditation app that makes meditation easy.
             
            
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                 I've been meditating on and off now for about 30 years,
             
            
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                 although I confess more off than on.
             
            
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                 And that's because I think like for a lot of people,
             
            
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                 sticking to a meditation practice can be pretty challenging.
             
            
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                 I started using Headspace a few years ago,
             
            
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                 and I found that it's really allowed me
             
            
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                 to stick to a meditation practice on a regular basis.
             
            
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                 I meditate anywhere from five to seven times a week.
             
            
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                 The app includes meditations that are all backed
             
            
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                 by scientific peer-reviewed studies,
             
            
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                 and it makes it really easy to start
             
            
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                 and complete the meditations.
             
            
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                 I started using these meditations
             
            
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                 while I was flying a few years back.
             
            
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                 On JetBlue flights,
             
            
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                 they started offering Headspace meditation,
             
            
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                 so that's where I initially started,
             
            
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                 and then I moved over to the app, and I really enjoy it,
             
            
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                 and I derive great benefit from it.
             
            
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                 If you'd like to try Headspace,
             
            
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                 you can go to headspace.com slash special offer,
             
            
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                 and if you do that, you'll get all the meditations
             
            
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                 that Headspace offers for free for one month.
             
            
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                 That's headspace.com slash special offer.
             
            
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                 You get all the meditations for free,
             
            
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                 which is the best offer that Headspace has
             
            
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                 available right now,
             
            
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                 so if you're interested in it, check it out.
             
            
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                 The second sponsor of today's podcast is Athletic Greens.
             
            
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                 Athletic Greens is an all-in-one
             
            
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                 vitamin mineral probiotic drink.
             
            
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                 I started using Athletic Greens in 2012,
             
            
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                 and I've been using it continuously ever since.
             
            
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                 I started using Athletic Greens
             
            
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                 because I found it rather dizzying to know
             
            
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                 which vitamins and minerals to take,
             
            
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                 and Athletic Greens allows me to get
             
            
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                 the full base of all the necessary vitamins and minerals
             
            
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                 in one easy-to-consume drink.
             
            
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                 It also turns out that the drink tastes quite good.
             
            
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                 I mix mine with some lemon juice and some water.
             
            
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                 I'll drink it once or twice a day.
             
            
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                 The probiotics in Athletic Greens are also important to me
             
            
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                 because there are a lot of data now
             
            
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                 supporting the fact that the gut microbiome
             
            
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                 is important for the gut-brain axis,
             
            
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                 for various aspects of cognitive function, immune function,
             
            
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                 metabolic function.
             
            
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                 There's just a huge number of things
             
            
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                 that having a healthy gut microbiome
             
            
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                 has been shown to be important for,
             
            
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                 so by taking Athletic Greens,
             
            
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                 I have that base covered as well.
             
            
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                 If you'd like to try Athletic Greens,
             
            
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                 you can go to athleticgreens.com slash Huberman,
             
            
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                 and if you do that, they'll give you a year's supply
             
            
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                 of liquid vitamin D3K2.
             
            
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                 There are also a lot of data now showing
             
            
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                 that vitamin D3 is very important
             
            
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                 for a number of different biological functions.
             
            
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                 In addition, they'll give you five free travel packs
             
            
            
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                 It can be difficult to mix up powders while on the road,
             
            
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                 you know, when in a car or, you know,
             
            
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                 in a hotel or on a plane, et cetera.
             
            
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                 The travel packs make everything really clean and easy,
             
            
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                 so you'll get the year supply of vitamin D3K2
             
            
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                 plus the five free travel packs
             
            
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                 if you go to athleticgreens.com slash Huberman.
             
            
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                 The third sponsor of today's podcast is Made For.
             
            
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                 Made For is a behavioral science company
             
            
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                 that makes learning positive habits and growth mindset easy.
             
            
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                 I've been involved with Made For since the beginning
             
            
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                 as the lead of their scientific advisory.
             
            
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                 Other members of the scientific advisory include,
             
            
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                 for instance, the head of the Chronobiology Unit
             
            
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                 at the National Institutes of Mental Health,
             
            
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                 as well as psychiatrists from Harvard Medical School
             
            
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                 and elsewhere, all of whom are serious about science
             
            
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                 and science-related tools for developing positive habits
             
            
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                 and growth mindset.
             
            
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                 The program is a 10-month program
             
            
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                 during which each month you engage in a specific activity
             
            
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                 designed to encourage and cultivate
             
            
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                 positive habits and growth mindset.
             
            
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                 As well, we hold a monthly Zoom call
             
            
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                 during which we discuss the program,
             
            
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                 people's progress, and answer any questions
             
            
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                 they have directly.
             
            
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                 If you'd like to try Made For,
             
            
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                 you can go to getmadefor.com,
             
            
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                 and if you put Huberman in at checkout,
             
            
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                 you'll get 20% off the program.
             
            
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                 That's getmadefor.com.
             
            
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                 Put Huberman in at checkout and get 20% off the program.
             
            
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                 Today, we're going to talk about
             
            
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                 how to change your nervous system for the better.
             
            
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                 As you recall, your nervous system
             
            
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                 includes your brain and your spinal cord,
             
            
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                 but also all the connections that your brain
             
            
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                 and spinal cord make with the organs of your body
             
            
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                 and all the connections that the organs of your body
             
            
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                 make with your brain and spinal cord.
             
            
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                 This thing that we call the nervous system
             
            
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                 is responsible for everything we know,
             
            
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                 all our behavior, all our emotions,
             
            
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                 everything we feel about ourselves and the outside world,
             
            
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                 everything we think and believe, it's really at the center
             
            
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                 of our entire experience of life and who we are.
             
            
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                 Fortunately, in humans, unlike in other species,
             
            
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                 we can change our nervous system
             
            
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                 by taking some very specific and deliberate actions.
             
            
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                 And today, we're really going to focus on the actions,
             
            
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                 the motor commands and the aspects of movement and balance
             
            
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                 that allow us to change our nervous system.
             
            
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                 It turns out that movement and balance
             
            
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                 actually provide windows or portals into our ability
             
            
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                 to change our nervous system the way we want,
             
            
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                 even if those changes are not about learning new movements
             
            
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                 or learning how to balance, and soon you'll understand why.
             
            
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                 So today, we're going to talk a lot
             
            
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                 about the basic science of neuroplasticity.
             
            
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                 I promise to not use excessive nomenclature,
             
            
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                 there'll be a little bit,
             
            
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                 but I'll try and make it as clear as possible.
             
            
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                 And we're also going to talk a lot about protocols and tools
             
            
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                 that the scientific literature points to and supports
             
            
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                 for changing our nervous system.
             
            
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                 Again, not just for sake of learning new motor movements
             
            
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                 or how to balance better, but for how to feel differently
             
            
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                 about particular experiences, both past, present and future,
             
            
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                 as well as how to learn faster.
             
            
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                 We're not going to discuss hacks, a word I loathe,
             
            
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                 we're not going to discuss gimmicks,
             
            
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                 we're going to discuss mechanism and scientific data
             
            
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                 and the tools that those mechanisms
             
            
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                 and scientific data point to
             
            
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                 so that you can tailor your practices around learning
             
            
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                 to your specific needs and goals.
             
            
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                 So let's begin by just examining the big picture question,
             
            
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                 which is does the brain control behavior?
             
            
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                 And my hope is that everyone is immediately thinking yes.
             
            
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                 The brain and nervous system, we really should say,
             
            
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                 because the brain is just one component of the nervous system
             
            
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                 controls our behavior.
             
            
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                 How does it do that?
             
            
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                 Well, there are a couple of different levels
             
            
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                 that it does that.
             
            
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                 First of all, if we're talking about movement,
             
            
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                 behavior generally means movement.
             
            
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                 If we're talking about movement,
             
            
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                 we have two categories of neurons that are very important
             
            
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                 to think about in the context of neuroplasticity.
             
            
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                 First of all, we have what are called lower motor neurons.
             
            
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                 These are motor neurons that live in our spinal cord.
             
            
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                 If for the aficionados out there,
             
            
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                 for those of you that might be head to medical school
             
            
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                 or just want to learn more about the anatomy,
             
            
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                 they live in the ventral horn of the spinal cord,
             
            
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                 but that doesn't matter.
             
            
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                 If you don't want to know that,
             
            
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                 just know that you have these things
             
            
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                 called lower motor neurons.
             
            
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                 These are neurons that are in the spinal cord,
             
            
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                 but they extend a wire that we call an axon
             
            
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                 out into the peripheral nervous system, into the body.
             
            
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                 And those neurons connect with muscle.
             
            
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                 They send electrical potentials out there
             
            
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                 that allow our muscles to twitch and to contract.
             
            
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                 As a little point of fact, actually,
             
            
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                 we don't have muscle memory.
             
            
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                 There's no such thing as muscle memory.
             
            
            
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                 They don't know anything.
             
            
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                 They don't have a history.
             
            
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                 They don't have a memory.
             
            
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                 They don't know anything.
             
            
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                 It is the neurons that control those muscles
             
            
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                 and their firing patterns in which all the information
             
            
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                 for motor patterns are stored.
             
            
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                 So your ability to walk is not muscle memory.
             
            
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                 It's neural memory.
             
            
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                 Now, the lower motor neurons,
             
            
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                 while smarter than the muscle, so to speak,
             
            
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                 are not the most brilliant of the motor neurons.
             
            
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                 They are generally involved in doing what they are told.
             
            
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                 And they are told what to do from two sources.
             
            
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                 We have circuits in our brainstem.
             
            
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                 So this would be kind of around your neck deep in the brain
             
            
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                 that are called central pattern generators.
             
            
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                 These are sometimes called CPGs.
             
            
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                 Central pattern generators are what allow us
             
            
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                 to generate repetitive patterns of movement.
             
            
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                 So inhaling and exhaling, inhaling and exhaling,
             
            
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                 subconsciously is controlled by a central pattern generator.
             
            
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                 That just means a collection of neurons.
             
            
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                 If you really want to know,
             
            
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                 they're called the pre-bot singer neurons
             
            
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                 discovered by Jack Feldman and colleagues at UCLA.
             
            
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                 These neurons in the brainstem send information
             
            
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                 down the phrenic nerve and control the diaphragm.
             
            
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                 So it goes inhale, exhale, inhale, exhale.
             
            
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                 And you don't have to think about that.
             
            
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                 You could think about it,
             
            
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                 and you could change the durations of inhales and exhales
             
            
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                 and change that up.
             
            
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                 But the motor neurons that control that
             
            
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                 are just responding to what the brain is telling it to do.
             
            
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                 The other central pattern generators
             
            
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                 include things like walking.
             
            
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                 The right limb, left limb, right limb, left limb pattern
             
            
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                 that we normally associate with walking
             
            
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                 was learned during childhood.
             
            
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                 And the central pattern generator, sometimes called CPGs,
             
            
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                 tell our lower motor neurons fire.
             
            
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                 Now you fire, now you fire.
             
            
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                 So they are literally saying right, left, right, left.
             
            
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                 They are the marching orders from the brainstem
             
            
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                 to the lower motor neurons.
             
            
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                 So these lower motor neurons do what they are told.
             
            
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                 They are obedient little soldiers
             
            
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                 and they do what they are told.
             
            
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                 And their job is to make the muscles
             
            
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                 contract at specific times.
             
            
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                 Okay, that's all simple.
             
            
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                 But then there are the upper motor neurons.
             
            
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                 The upper motor neurons actually reside in our motor cortex
             
            
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                 way up on top of the brain.
             
            
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                 And they are involved in sending signals
             
            
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                 for deliberate action.
             
            
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                 Okay, so they send signals to the lower motor neurons
             
            
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                 which are the effectors,
             
            
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                 the ones that actually control the muscles,
             
            
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                 but the upper motor neurons are the ones
             
            
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                 that send very specific signals.
             
            
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                 For instance, the signals that would allow you
             
            
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                 to make a cup of coffee in the morning
             
            
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                 or to deliberately engage in any kind of behavior.
             
            
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                 Now you can probably make a cup of coffee in the morning
             
            
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                 without having to think about it too much.
             
            
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                 It's almost reflexive for you now,
             
            
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                 which means that a lot of the information
             
            
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                 about how to perform that particular movement
             
            
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                 has been passed off to circuitry
             
            
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                 that's now more or less in the brainstem
             
            
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                 and below the motor cortex.
             
            
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                 Now, why am I giving you all this detail?
             
            
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                 Well, if you want to change motor patterns,
             
            
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                 you have to know where in the circuitry changes are possible
             
            
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                 and you ought to know where the changes
             
            
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                 are most likely to occur.
             
            
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                 You also need to know how do you signal
             
            
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                 to the brain and nervous system that a change is necessary.
             
            
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                 So let's just pause there,
             
            
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                 return to the initial question that we started with,
             
            
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                 which is does the brain control behavior?
             
            
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                 And the answer is yes, and now you know how.
             
            
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                 It's upper motor neurons, lower motor neurons.
             
            
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                 You've got these things called central pattern generators
             
            
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                 and some connection with the muscle.
             
            
            
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                 So we've just got basically what was the equivalent
             
            
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                 of the introduction to a college lecture
             
            
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                 on motor control in the nervous system,
             
            
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                 but the point today is all about plasticity.
             
            
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                 How can that be leveraged in order to open up
             
            
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                 this magical thing that we call plasticity
             
            
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                 in order to access changes to our emotional experience
             
            
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                 or to our belief system or to our ability to remember
             
            
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                 and use specific kinds of information
             
            
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                 for say math or language, et cetera?
             
            
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                 Well, what I'm not going to tell you
             
            
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                 is that you need to go running or you need to go biking
             
            
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                 or that simply going through motor patterns
             
            
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                 is going to open up plasticity,
             
            
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                 because I hate to tell you this,
             
            
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                 but as beneficial as exercise is,
             
            
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                 it does not open plasticity unless you do certain things.
             
            
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                 And I will tell you exactly
             
            
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                 what those certain things are today.
             
            
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                 To be clear, I think exercise is wonderful and healthy,
             
            
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                 can improve cardiovascular function,
             
            
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                 maintain strength, bone density, all that good stuff,
             
            
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                 but just working out or doing your exercise
             
            
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                 of various kinds will not change your nervous system.
             
            
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                 It will maintain it
             
            
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                 and it can certainly improve other health metrics,
             
            
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                 but it is not going to open up the window for plasticity.
             
            
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                 The question we need to ask
             
            
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                 is can behavior change the brain?
             
            
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                 We already agreed that the brain can change behavior,
             
            
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                 but can behavior change the brain?
             
            
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                 And the answer is yes,
             
            
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                 provided that behavior is different enough in specific ways
             
            
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                 from the behaviors that you already know how to perform.
             
            
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                 Let me repeat that.
             
            
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                 Can behavior change the brain?
             
            
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                 And the answer is yes,
             
            
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                 provided that behavior is different enough
             
            
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                 from the sorts of behaviors
             
            
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                 that you already know how to perform.
             
            
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                 And I should have added the word well,
             
            
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                 because you can't obviously perform a behavior
             
            
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                 that you don't know how to perform
             
            
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                 because you don't know how to do it yet.
             
            
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                 But there's a key element to accessing neuroplasticity
             
            
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                 that frankly, I don't see out there
             
            
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                 in the general discussion about neuroplasticity.
             
            
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                 In the general discussion about neuroplasticity
             
            
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                 and about learning, I hear all these gimmicks
             
            
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                 about using different ways to remember
             
            
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                 lots of people's names
             
            
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                 and arranging things into their first letters
             
            
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                 and mnemonics and all this kind of stuff,
             
            
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                 which frankly to me feels really gimmicky.
             
            
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                 And I think that if you look at super learners,
             
            
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                 they tend to be people that have a process
             
            
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                 of say extreme memory,
             
            
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                 but people who have extreme memory,
             
            
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                 generally the literature shows us
             
            
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                 are pretty poor at other things.
             
            
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                 So I don't think most of us are interested
             
            
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                 in walking around knowing how to remember everything.
             
            
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                 In fact, there are some interesting studies
             
            
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                 looking at humans who over-remember
             
            
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                 and they suffer tremendously
             
            
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                 because they remember all sorts of things
             
            
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                 like the number at the top of the receipt at the bodega
             
            
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                 that they bought at Coca-Cola 10 years ago.
             
            
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                 This is useless information for most people.
             
            
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                 They don't do well in life really.
             
            
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                 So the goal isn't to remember everything,
             
            
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                 the goal is to be selective about your brain changes.
             
            
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                 And when we talk about brain changes,
             
            
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                 I want to highlight adaptive changes.
             
            
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                 There's a whole category of things
             
            
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                 that we're going to discuss
             
            
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                 when we talk about traumatic brain injury and dementia,
             
            
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                 a topic for a future episode,
             
            
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                 about all the things that happen when you have damaged
             
            
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                 your nervous system or you're missing neurons.
             
            
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                 But today I really want to talk about something
             
            
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                 that I think is very near and dear to many of your hearts,
             
            
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                 which is what are the behaviors that you can engage in
             
            
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                 to access neuroplasticity
             
            
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                 so that then you can apply that plasticity
             
            
                link |
                
                 to the specific things that you want to learn or unlearn.
             
            
                link |
                
                 This is very important because I don't want people
             
            
                link |
                
                 to get the impression that we're really talking
             
            
                link |
                
                 about learning a bunch of motor movements.
             
            
                link |
                
                 You may be an athlete, you might not be an athlete.
             
            
                link |
                
                 You might want to learn how to dance, you might not.
             
            
                link |
                
                 You might want to learn how to dance
             
            
                link |
                
                 and get better at remembering and learning languages,
             
            
                link |
                
                 for instance, or at unlearning
             
            
                link |
                
                 some difficult emotional experience,
             
            
                link |
                
                 meaning you want to remove the emotional load
             
            
                link |
                
                 from a particular memory of an experience.
             
            
                link |
                
                 What we're talking about today is using behavior
             
            
                link |
                
                 as a gate to enter states of mind and body
             
            
                link |
                
                 that allow you to access plasticity.
             
            
                link |
                
                 So let's talk about the different kinds of plasticity
             
            
                link |
                
                 that are available to us,
             
            
                link |
                
                 because those will point directly
             
            
                link |
                
                 towards the type of protocols that we should engage in
             
            
                link |
                
                 to change ourselves for the better,
             
            
                link |
                
                 the so-called adaptive plasticity.
             
            
                link |
                
                 There is something called representational plasticity.
             
            
                link |
                
                 Representational plasticity
             
            
                link |
                
                 is just your internal representation of the outside world.
             
            
                link |
                
                 So you have a map of auditory space, believe it or not,
             
            
                link |
                
                 meaning you have neurons that respond
             
            
                link |
                
                 when something over on my right happens,
             
            
                link |
                
                 like I'm snapping my fingers over to my right,
             
            
                link |
                
                 can't snap as well on my left,
             
            
                link |
                
                 which is the whole thing into itself.
             
            
                link |
                
                 Yeah, weak over there on the left side.
             
            
                link |
                
                 But when I do that,
             
            
                link |
                
                 there are different neurons respond to those.
             
            
                link |
                
                 We have a map of visual space.
             
            
                link |
                
                 Certain neurons are seeing things
             
            
                link |
                
                 in certain portions of visual space and not others.
             
            
                link |
                
                 We have a map of motor space,
             
            
                link |
                
                 meaning when we move our limbs in particular directions,
             
            
                link |
                
                 we know where those limbs are,
             
            
                link |
                
                 because even if we can't see them,
             
            
                link |
                
                 we have what's called proprioceptive feedback.
             
            
                link |
                
                 So we have knowledge about where our limbs are.
             
            
                link |
                
                 In fact, people that lack certain neurons
             
            
                link |
                
                 for proprioceptive feedback,
             
            
                link |
                
                 they are very poor at controlling their motor behavior.
             
            
                link |
                
                 They get injured a lot.
             
            
                link |
                
                 It's actually a terrible situation.
             
            
                link |
                
                 So we've got all these representations inside,
             
            
                link |
                
                 and we have maps of our motor commands.
             
            
                link |
                
                 We know that, for instance,
             
            
                link |
                
                 if I want to reach out and grab the pen in front of me,
             
            
                link |
                
                 that I need to generate a certain amount of force,
             
            
                link |
                
                 so I rarely overshoot.
             
            
                link |
                
                 I rarely miss the pen, okay?
             
            
                link |
                
                 So our maps of the motor world
             
            
                link |
                
                 and our maps of the sensory world are merged.
             
            
                link |
                
                 The way to create plasticity
             
            
                link |
                
                 is to create mismatches or errors in how we perform things.
             
            
                link |
                
                 And this, I think, is an amazing and important feature
             
            
                link |
                
                 of neuroplasticity that is highly underappreciated.
             
            
                link |
                
                 The way to create plasticity
             
            
                link |
                
                 is to send signals to the brain that something is wrong,
             
            
                link |
                
                 something is different, and something isn't being achieved.
             
            
                link |
                
                 I think this will completely reframe
             
            
                link |
                
                 the way that most people think about plasticity.
             
            
                link |
                
                 Most of us think about plasticity as,
             
            
                link |
                
                 okay, we're going to get into this optimal learning state
             
            
                link |
                
                 or flow, and then suddenly we're going to be able
             
            
                link |
                
                 to do all the things that we wish that we could do.
             
            
                link |
                
                 Well, I hate to break it to you,
             
            
                link |
                
                 but flow is an expression of what we already know how to do.
             
            
                link |
                
                 It is not a state for learning.
             
            
                link |
                
                 And I'm willing to go to bat
             
            
                link |
                
                 with any of the flow anistas out there
             
            
                link |
                
                 that want to challenge me on that one.
             
            
                link |
                
                 Flow is an expression of nervous system capabilities
             
            
                link |
                
                 that are already embedded in us.
             
            
                link |
                
                 Errors and making errors out of sync
             
            
                link |
                
                 with what we would like to do
             
            
                link |
                
                 is how our nervous system is cued
             
            
                link |
                
                 through very distinct biological mechanisms
             
            
                link |
                
                 that something isn't going right,
             
            
                link |
                
                 and therefore certain neurochemicals are deployed
             
            
                link |
                
                 that'll signal the neural circuits that they have to change.
             
            
                link |
                
                 So let's talk about the experiments
             
            
                link |
                
                 that support what I just said,
             
            
                link |
                
                 because I'm about to tell you that making errors
             
            
                link |
                
                 over and over and over again
             
            
                link |
                
                 is the route to shaping your nervous system
             
            
                link |
                
                 so that it performs better and better and better.
             
            
                link |
                
                 And I'm not going to tell you that the last rep of a set
             
            
                link |
                
                 where you hit failure in the gym
             
            
                link |
                
                 is anything like neuroplasticity.
             
            
                link |
                
                 You hear that too, that it's pushing to that point
             
            
                link |
                
                 of a cliff where you just can't function anymore.
             
            
                link |
                
                 That's the signal, that's not the signal.
             
            
                link |
                
                 That's a distinct neuromuscular phenomenon
             
            
                link |
                
                 that bears zero resemblance
             
            
                link |
                
                 to what it takes to get neuroplasticity.
             
            
                link |
                
                 So let's talk about errors and making errors
             
            
                link |
                
                 and why and how that triggers the release of chemicals
             
            
                link |
                
                 that then allow us to not just learn the thing
             
            
                link |
                
                 that we're doing in the motor sense,
             
            
                link |
                
                 play the piano, dance, et cetera,
             
            
                link |
                
                 but it also creates an environment to milieu within the brain
             
            
                link |
                
                 that allows us to then go learn how to couple
             
            
                link |
                
                 or uncouple a particular emotion to an experience
             
            
                link |
                
                 or better language learning or better mathematical learning.
             
            
                link |
                
                 It's a really fundamental aspect of how we're built.
             
            
                link |
                
                 And when you look at it,
             
            
                link |
                
                 it's actually very straightforward.
             
            
                link |
                
                 It's a series of logical steps
             
            
                link |
                
                 that once you learn how to open those hatches,
             
            
                link |
                
                 it becomes very straightforward to deploy.
             
            
                link |
                
                 Last episode, we discussed some of the basic principles
             
            
                link |
                
                 of neuroplasticity.
             
            
                link |
                
                 If you didn't hear that episode, no problem.
             
            
                link |
                
                 I'll just review it quickly,
             
            
                link |
                
                 which is that it's a falsehood that everything that we do
             
            
                link |
                
                 and experience changes our brain.
             
            
                link |
                
                 The brain changes when certain neurochemicals,
             
            
                link |
                
                 namely acetylcholine, epinephrine, and dopamine
             
            
                link |
                
                 are released in ways and in the specific times
             
            
                link |
                
                 that allow for neural circuits to be marked for change
             
            
                link |
                
                 and then the change occurs later during sleep.
             
            
                link |
                
                 I'll review that later,
             
            
                link |
                
                 but basically you need a certain cocktail of chemicals
             
            
                link |
                
                 released in the brain in order for a particular behavior
             
            
                link |
                
                 to reshape the way that our brain works.
             
            
                link |
                
                 So the question really is,
             
            
                link |
                
                 what allows those neurochemicals to be released?
             
            
                link |
                
                 And last episode, it talked all about focus.
             
            
                link |
                
                 If you haven't seen or heard that episode,
             
            
                link |
                
                 you might want to check it out
             
            
                link |
                
                 about some specific tools and practices
             
            
                link |
                
                 that can allow you to build up your capacity for focus
             
            
                link |
                
                 and release certain chemicals in that cocktail.
             
            
                link |
                
                 But today we're going to talk about the other chemicals
             
            
                link |
                
                 in the cocktail, in particular dopamine.
             
            
                link |
                
                 And we're really going to center our discussion
             
            
                link |
                
                 around this issue of making errors
             
            
                link |
                
                 and why making errors is actually the signal
             
            
                link |
                
                 that tells the brain, okay, it's time to change,
             
            
                link |
                
                 or more generally, it's time to pay attention to things
             
            
                link |
                
                 so that you change.
             
            
                link |
                
                 And I really want to distinguish this point really clearly,
             
            
                link |
                
                 which is that I'm going to talk today a lot about motor
             
            
                link |
                
                 and vestibular, meaning balance programs,
             
            
                link |
                
                 but not just for learning motor commands and balance,
             
            
                link |
                
                 not just for learning new motor skills and balance,
             
            
                link |
                
                 but also for setting a stage or a kind of condition
             
            
                link |
                
                 in your brain where you can go learn other things as well.
             
            
                link |
                
                 So let's talk about some classic experiments
             
            
                link |
                
                 that really nail down what's most important
             
            
                link |
                
                 in this discussion about plasticity.
             
            
                link |
                
                 So I mentioned last episode,
             
            
                link |
                
                 and I'll just tell you right now, again,
             
            
                link |
                
                 the brain is incredibly plastic from about birth
             
            
                link |
                
                 until about age 25.
             
            
                link |
                
                 Passive experience will shape the brain
             
            
                link |
                
                 just because of the way that the chemicals
             
            
                link |
                
                 that are sloshing around in there
             
            
                link |
                
                 and the way that the neurons are arranged
             
            
                link |
                
                 and all sorts of things.
             
            
                link |
                
                 The brain's job is to customize itself
             
            
                link |
                
                 in response to its experience.
             
            
                link |
                
                 And then somewhere about 25,
             
            
                link |
                
                 it's not like the day after your 26th birthday,
             
            
                link |
                
                 plasticity closes.
             
            
                link |
                
                 There's a kind of tapering off of plasticity,
             
            
                link |
                
                 and you need different mechanisms
             
            
                link |
                
                 to engage plasticity as an adult.
             
            
                link |
                
                 We're mostly going to be talking about adult plasticity today
             
            
                link |
                
                 but I got a lot of questions about,
             
            
                link |
                
                 well, what about if I'm younger than 25?
             
            
                link |
                
                 Well, first of all, that's great.
             
            
                link |
                
                 I wish I had a time machine, but I don't.
             
            
                link |
                
                 Because as I've said before,
             
            
                link |
                
                 the stinger is when you're young,
             
            
                link |
                
                 your brain is very plastic,
             
            
                link |
                
                 but you have less control over your experience.
             
            
                link |
                
                 When you're older,
             
            
                link |
                
                 generally you have more control over your experience,
             
            
                link |
                
                 but your brain is less plastic.
             
            
                link |
                
                 So if you're already asking the question
             
            
                link |
                
                 as a 20-year-old or a 15-year-old,
             
            
                link |
                
                 what can I do now that's really gonna enhance my brain?
             
            
                link |
                
                 I guess the simple question would answer,
             
            
                link |
                
                 excuse me, would be an aside
             
            
                link |
                
                 which we get the broadest education you can possible.
             
            
                link |
                
                 That means math, chemistry, physics, literature, music,
             
            
                link |
                
                 learn how to play an instrument.
             
            
                link |
                
                 I'm saying that because I wish I had, et cetera.
             
            
                link |
                
                 Get a broad training in a number of things
             
            
                link |
                
                 and find the thing that really captures your passion
             
            
                link |
                
                 and excitement and then put a ton of additional effort there.
             
            
                link |
                
                 That's what I recommend, including emotional development.
             
            
                link |
                
                 Maybe a topic for a future episode.
             
            
                link |
                
                 But if you are an adult or if you are a young person,
             
            
                link |
                
                 knowing how to tap into these plasticity mechanisms
             
            
            
                link |
                
                 You need these chemicals deployed in the nervous system
             
            
                link |
                
                 in order to mark whatever nerve cells happen to be firing
             
            
                link |
                
                 in the time afterward for change.
             
            
                link |
                
                 And people are obsessed with asking,
             
            
                link |
                
                 what supplements, what drugs, what conditions,
             
            
                link |
                
                 what machines will allow for that?
             
            
                link |
                
                 But there's a natural set of conditions that allow for that.
             
            
                link |
                
                 When we came into this world,
             
            
                link |
                
                 we learned to take our different maps of experience,
             
            
                link |
                
                 our motor maps, our auditory maps, our visual maps,
             
            
                link |
                
                 and to link them, we align those maps.
             
            
                link |
                
                 The simplest example is the one I gave before.
             
            
                link |
                
                 If I hear something off to my right, like a click,
             
            
                link |
                
                 like that, it could come from my finger snapping
             
            
                link |
                
                 or it could come from something generated by somebody else
             
            
                link |
                
                 or something else to my right, I look to my right.
             
            
                link |
                
                 If I hear it on the left, I look to my left.
             
            
                link |
                
                 If I hear it right in front of me,
             
            
                link |
                
                 I keep looking right in front of me.
             
            
                link |
                
                 And if I hear it behind me, I turn around.
             
            
                link |
                
                 And that's because our maps of visual space
             
            
                link |
                
                 and our maps of auditory space and our maps of motor space
             
            
                link |
                
                 are aligned to one another in perfect register.
             
            
                link |
                
                 It's an incredible feature of our nervous system.
             
            
                link |
                
                 It takes place in a structure called the superior colliculus,
             
            
                link |
                
                 although you don't need to know that name.
             
            
                link |
                
                 Superior colliculus has layers,
             
            
                link |
                
                 literally stacks of neurons like in a sandwich
             
            
                link |
                
                 where the zero point right in front of me,
             
            
                link |
                
                 or maybe 10 or 15 degrees off to my right
             
            
                link |
                
                 or 10 or 15 degrees off to my left
             
            
                link |
                
                 are aligned so that the auditory neurons,
             
            
                link |
                
                 the ones that care about sounds at 15 degrees to my right,
             
            
                link |
                
                 sit directly below the neurons that look at 15 degrees
             
            
                link |
                
                 to my right in my visual system.
             
            
                link |
                
                 And when I reach over to this direction,
             
            
                link |
                
                 there's a signal that's sent down through those layers
             
            
                link |
                
                 that says 15 degrees off to the right
             
            
                link |
                
                 is the direction to look, it's the direction to listen,
             
            
                link |
                
                 and it's the direction to move if I need to move.
             
            
                link |
                
                 So there's an alignment, and this is really powerful.
             
            
                link |
                
                 And this is what allows us to move through space
             
            
                link |
                
                 and function in our lives in a really fluid way.
             
            
                link |
                
                 It's set up during development,
             
            
                link |
                
                 but there have been some important experiments
             
            
                link |
                
                 that have revealed that these maps are plastic,
             
            
                link |
                
                 meaning they can shift, they're subject to neuroplasticity,
             
            
                link |
                
                 and there are specific rules that allow us to shift them.
             
            
                link |
                
                 So here's the key experiment.
             
            
                link |
                
                 The key experiment was done by a colleague of mine,
             
            
                link |
                
                 who's now retired, but whose work is absolutely fundamental
             
            
                link |
                
                 in the field of neuroplasticity, Eric Knudsen.
             
            
                link |
                
                 The Knudsen lab and many of the Knudsen lab
             
            
                link |
                
                 scientific offspring showed that if one
             
            
                link |
                
                 is to wear prism glasses that shift the visual field,
             
            
                link |
                
                 that eventually there'll be a shift
             
            
                link |
                
                 in the representation of the auditory and motor maps too.
             
            
                link |
                
                 Now, what they initially did
             
            
                link |
                
                 is they looked at young subjects,
             
            
                link |
                
                 and what they did is they moved the visual world
             
            
                link |
                
                 by making them wear prism glasses,
             
            
                link |
                
                 so that for instance, if my pen is out in front of me
             
            
                link |
                
                 at five degrees off center,
             
            
                link |
                
                 so just a little bit off center,
             
            
                link |
                
                 if you're listening to this,
             
            
                link |
                
                 this would be like just a little bit to my right,
             
            
                link |
                
                 but in these prism glasses,
             
            
                link |
                
                 I actually see that pen way over far on my right,
             
            
                link |
                
                 so it's actually here, but I see it over there
             
            
                link |
                
                 because I'm wearing prisms on my eyes.
             
            
                link |
                
                 What happens is in the first day or so,
             
            
                link |
                
                 you ask people or you ask animal subjects or whatever
             
            
                link |
                
                 to reach for this object,
             
            
                link |
                
                 and they reach to the wrong place
             
            
                link |
                
                 because they're seeing it where it isn't.
             
            
                link |
                
                 This gets especially complicated
             
            
                link |
                
                 when you start including sounds,
             
            
                link |
                
                 when you have a thing off to your right making a sound,
             
            
                link |
                
                 but the thing is actually right here,
             
            
                link |
                
                 so you're hearing the sound at one location
             
            
                link |
                
                 and you're seeing the object at another location
             
            
                link |
                
                 because you're wearing these prisms,
             
            
                link |
                
                 so your image of the world is totally distorted.
             
            
                link |
                
                 Or in experiments done by other groups,
             
            
                link |
                
                 they wear glasses, subjects wear glasses
             
            
                link |
                
                 that completely invert the visual world
             
            
                link |
                
                 so that everything is upside down,
             
            
                link |
                
                 which is an extreme example of these representational maps
             
            
                link |
                
                 being flipped or shifted.
             
            
                link |
                
                 But what you find is that in young individuals,
             
            
                link |
                
                 within a day or two,
             
            
                link |
                
                 they start adjusting their motor behavior
             
            
                link |
                
                 in exactly the right way
             
            
                link |
                
                 so that they always reach to the correct location.
             
            
                link |
                
                 So they hear a sound at one location,
             
            
                link |
                
                 they see the object that ought to make that sound
             
            
                link |
                
                 at a different location,
             
            
                link |
                
                 and they somehow are able to adjust their motor behavior
             
            
                link |
                
                 to reach to the correct location.
             
            
                link |
                
                 It's incredible, it's absolutely incredible.
             
            
                link |
                
                 Or in the case of the people
             
            
                link |
                
                 who look at the world upside down,
             
            
                link |
                
                 they somehow are able to navigate this upside down world
             
            
                link |
                
                 even though we're completely used to
             
            
                link |
                
                 our feet being on the floor and not on the ceiling
             
            
                link |
                
                 and people not walking at us
             
            
                link |
                
                 by hanging off the ceiling like bats, amazing.
             
            
                link |
                
                 And what it tells us is that these maps
             
            
                link |
                
                 that are aligned to one another
             
            
                link |
                
                 can move and shift and rotate and even flip themselves.
             
            
                link |
                
                 And it happens best in young individuals.
             
            
                link |
                
                 If you do this in older individuals,
             
            
                link |
                
                 in most cases it takes a very long time
             
            
                link |
                
                 for the maps to shift and in some cases they never shift.
             
            
                link |
                
                 So this is a very experimental scenario
             
            
                link |
                
                 but it's an important one to understand
             
            
                link |
                
                 because it really tamps down the fact
             
            
                link |
                
                 that we have the capacity to create dramatic shifts
             
            
                link |
                
                 in our representation of the outside world.
             
            
                link |
                
                 So how can we get plasticity as adult
             
            
                link |
                
                 that mimics the plasticity that we get when we are juveniles?
             
            
                link |
                
                 Well, the Knudsen lab and other labs have looked at this
             
            
                link |
                
                 and it's really interesting.
             
            
                link |
                
                 First of all, we have to ask
             
            
                link |
                
                 what is the signal for plasticity?
             
            
                link |
                
                 Is it just having prism glasses on?
             
            
                link |
                
                 No, because they did that experiment and ruled that out.
             
            
                link |
                
                 Is it just the fact that the visual thing is over to my,
             
            
                link |
                
                 appears to be far over to my right
             
            
                link |
                
                 when in fact it's right in front of me?
             
            
                link |
                
                 No, the signal that generates the plasticity
             
            
                link |
                
                 is the making of errors.
             
            
                link |
                
                 It's the reaches and failures
             
            
                link |
                
                 that signal to the nervous system that this is not working
             
            
                link |
                
                 and therefore the shifts start to take place.
             
            
                link |
                
                 And this is so fundamentally important
             
            
                link |
                
                 because I think most people think,
             
            
                link |
                
                 oh, well, practice is gonna be,
             
            
                link |
                
                 I have to access beginner's mind,
             
            
                link |
                
                 which is a great concept actually.
             
            
                link |
                
                 It's about approaching things, expecting to make errors,
             
            
            
                link |
                
                 I think I am a believer in beginner's mind,
             
            
                link |
                
                 but people understandably get frustrated.
             
            
                link |
                
                 Like they're trying to learn a piece on the piano
             
            
                link |
                
                 and they don't know, they can't do it
             
            
                link |
                
                 or they're trying to write a piece of code
             
            
                link |
                
                 or they're trying to access some sort of motor behavior
             
            
                link |
                
                 and they can't do it.
             
            
                link |
                
                 And the frustration drives them crazy.
             
            
                link |
                
                 And like, I can't do it, I can't do it.
             
            
                link |
                
                 When they don't realize that the errors themselves
             
            
                link |
                
                 are signaling to the brain and nervous system,
             
            
                link |
                
                 something's not working.
             
            
                link |
                
                 And of course the brain doesn't understand the words,
             
            
                link |
                
                 something isn't working.
             
            
                link |
                
                 The brain doesn't even understand frustration
             
            
                link |
                
                 as an emotional state.
             
            
                link |
                
                 The brain understands the neurochemicals that are released,
             
            
                link |
                
                 namely epinephrine and acetylcholine,
             
            
                link |
                
                 but also, and we'll get into this, the molecule dopamine,
             
            
                link |
                
                 when we start to approximate the correct behavior
             
            
                link |
                
                 just a little bit and we start getting a little bit right.
             
            
                link |
                
                 So what happens is when we make errors,
             
            
                link |
                
                 the nervous system kind of, I don't wanna say freaks out
             
            
                link |
                
                 because it's a very mechanistic and controlled situation,
             
            
                link |
                
                 but the nervous system starts releasing neurotransmitters
             
            
                link |
                
                 and neuromodulators that say,
             
            
                link |
                
                 we better change something in the circuitry.
             
            
                link |
                
                 And so errors are the basis for neuroplasticity
             
            
            
                link |
                
                 And I wish that this was more prominent out there.
             
            
                link |
                
                 I guess this is why I'm saying it.
             
            
                link |
                
                 And humans do not like this feeling of frustration
             
            
                link |
                
                 and making errors.
             
            
                link |
                
                 The few that do, do exceedingly well in whatever pursuits
             
            
                link |
                
                 they happen to be involved in.
             
            
                link |
                
                 The ones that don't generally don't do well.
             
            
                link |
                
                 They generally don't learn much.
             
            
                link |
                
                 And if you think about it,
             
            
                link |
                
                 why would your nervous system ever change?
             
            
                link |
                
                 Why would it ever change?
             
            
                link |
                
                 Unless there was something to be afraid of,
             
            
                link |
                
                 something that made us feel awful will signal
             
            
                link |
                
                 that the nervous system needs to change,
             
            
                link |
                
                 or there's an error in our performance.
             
            
                link |
                
                 So it turns out that the feedback of these errors,
             
            
                link |
                
                 the reaching to the wrong location
             
            
                link |
                
                 starts to release a number of things.
             
            
                link |
                
                 And now you've heard about them many times,
             
            
                link |
                
                 but this would be epinephrine, it increases alertness,
             
            
                link |
                
                 acetylcholine focus.
             
            
                link |
                
                 And this is why frustration that leads us
             
            
                link |
                
                 to just kind of quit and walk away from the endeavor
             
            
                link |
                
                 is the absolute worst thing.
             
            
                link |
                
                 But because if acetylcholine is released,
             
            
                link |
                
                 it creates an opportunity to focus on the error margin,
             
            
                link |
                
                 the distance between what it is that you're doing
             
            
                link |
                
                 and what it is that you would like to do.
             
            
                link |
                
                 And then the nervous system starts to make changes
             
            
                link |
                
                 almost immediately in order to try
             
            
                link |
                
                 and get the behavior right.
             
            
                link |
                
                 And when you start getting it even a little bit right,
             
            
                link |
                
                 that third molecule comes online or is released,
             
            
                link |
                
                 which is dopamine,
             
            
                link |
                
                 which allows for the plastic changes to occur very fast.
             
            
                link |
                
                 Now, this is what all happens very naturally
             
            
                link |
                
                 in young brains, but in old brains,
             
            
                link |
                
                 it tends to be pretty slow except for in two conditions.
             
            
                link |
                
                 So let me just pause and just say this.
             
            
                link |
                
                 If you are uncomfortable making errors
             
            
                link |
                
                 and you get frustrated easily,
             
            
                link |
                
                 if you leverage that frustration
             
            
                link |
                
                 toward drilling deeper into the endeavor,
             
            
                link |
                
                 you are setting yourself up
             
            
                link |
                
                 for a terrific set of plasticity mechanisms to engage.
             
            
                link |
                
                 But if you take that frustration
             
            
                link |
                
                 and you walk away from the endeavor,
             
            
                link |
                
                 you are essentially setting up plasticity
             
            
                link |
                
                 to rewire you according to what happens afterwards,
             
            
                link |
                
                 which is generally feeling pretty miserable.
             
            
                link |
                
                 So now you can kind of start to appreciate why it is
             
            
                link |
                
                 that continuing to drill into a process
             
            
                link |
                
                 to the point of frustration,
             
            
                link |
                
                 but then staying with that process for a little bit longer,
             
            
                link |
                
                 and I'll define exactly what I mean by a little bit,
             
            
                link |
                
                 is the most important thing for adult learning,
             
            
                link |
                
                 as well as childhood learning,
             
            
                link |
                
                 but adult learning in particular.
             
            
                link |
                
                 Now, the Newton Lab did two very important
             
            
                link |
                
                 sets of experiments.
             
            
                link |
                
                 The first one was published in Nature,
             
            
                link |
                
                 very important study,
             
            
                link |
                
                 which showed that juveniles can make these massive shifts
             
            
                link |
                
                 in their map representations,
             
            
                link |
                
                 meaning you can shift the visual world using visual prisms
             
            
            
                link |
                
                 and very quickly young individuals
             
            
                link |
                
                 can shift their representations of the world
             
            
                link |
                
                 so that they learn to reach to the correct location.
             
            
                link |
                
                 They get a lot of plasticity all at once,
             
            
                link |
                
                 and it happens very fast
             
            
                link |
                
                 in the period of just a couple of days.
             
            
                link |
                
                 In adults, it tends to be very slow,
             
            
                link |
                
                 and most individuals never actually accomplish
             
            
                link |
                
                 the full map shift.
             
            
                link |
                
                 They don't get the plasticity.
             
            
                link |
                
                 And here, we're talking about map shifts,
             
            
                link |
                
                 but this could be learning a new language.
             
            
                link |
                
                 This could be any number of different things
             
            
                link |
                
                 that one were attempting.
             
            
                link |
                
                 So what we're saying is what I already said before,
             
            
                link |
                
                 which is that we learn very well as youngsters,
             
            
                link |
                
                 but not as adults after 25.
             
            
                link |
                
                 But then what they did
             
            
                link |
                
                 is they started making the increment of change smaller.
             
            
                link |
                
                 So instead of shifting the world a huge amount
             
            
                link |
                
                 by putting prisms that shifted the visual world
             
            
                link |
                
                 all the way over to the right,
             
            
                link |
                
                 they did this incrementally.
             
            
                link |
                
                 So first, they put on prisms
             
            
                link |
                
                 that shifted it just a little bit,
             
            
                link |
                
                 just like seven degrees, I believe was the exact number.
             
            
                link |
                
                 And then it was 14 degrees, and then it was 28 degrees.
             
            
                link |
                
                 And so what they found was that the adult nervous system
             
            
                link |
                
                 can tolerate smaller and smaller errors over time,
             
            
                link |
                
                 but that you can stack those errors
             
            
                link |
                
                 so that you can get a lot of plasticity.
             
            
                link |
                
                 Put simply, incremental learning as an adult
             
            
                link |
                
                 is absolutely essential.
             
            
                link |
                
                 You are not gonna get massive shifts
             
            
                link |
                
                 in your representations of the outside world.
             
            
                link |
                
                 So how do you make small errors as opposed to big errors?
             
            
                link |
                
                 Well, the key is smaller bouts of focused learning
             
            
                link |
                
                 for smaller bits of information.
             
            
                link |
                
                 It's a mistake to try and learn a lot of information
             
            
                link |
                
                 in one learning bout as an adult.
             
            
                link |
                
                 What these papers from the Knudsen Lab show
             
            
                link |
                
                 and what others have gone on to show
             
            
                link |
                
                 is that the adult nervous system is fully capable
             
            
                link |
                
                 of engaging in a huge amount of plasticity,
             
            
                link |
                
                 but you need to do it in smaller increments
             
            
                link |
                
                 per learning epoch or per learning episode.
             
            
                link |
                
                 So how would you do this?
             
            
                link |
                
                 Well, let's say, for instance, I'm terrible at free throws.
             
            
                link |
                
                 So let's say I wanted to learn free throws.
             
            
                link |
                
                 I'm 45 years old, so I'm well past the 25 and under mark.
             
            
                link |
                
                 I'm gonna make errors, I'm gonna make a lot of errors.
             
            
                link |
                
                 If I go into learning free throws,
             
            
                link |
                
                 knowing that errors are the gate to plasticity,
             
            
                link |
                
                 well, then I feel a little bit better,
             
            
                link |
                
                 but I still have to aim for the rim of the basket
             
            
                link |
                
                 or the net, basically showing how little
             
            
                link |
                
                 I know about basketball.
             
            
                link |
                
                 But I think I know the general themes around basketball.
             
            
                link |
                
                 It involves a net, a backboard, and a ball, of course.
             
            
                link |
                
                 So I go to the free throw line and I'll throw.
             
            
                link |
                
                 How long should I go?
             
            
                link |
                
                 Well, until I'm hitting the point of frustration,
             
            
                link |
                
                 and at that point, continuing probably for anywhere
             
            
                link |
                
                 from 10 to 100 more trials should be my limit, right?
             
            
                link |
                
                 That should be my limit if I want to improve
             
            
                link |
                
                 some specific aspect of the motor behavior.
             
            
                link |
                
                 And so the question then is,
             
            
                link |
                
                 what should I be paying attention to?
             
            
                link |
                
                 What should I be focusing on?
             
            
                link |
                
                 Well, obviously trying to get the ball into the basket,
             
            
                link |
                
                 but the beauty of motor learning is that the circuits
             
            
                link |
                
                 for auditory and visual and motor
             
            
                link |
                
                 more or less teach themselves.
             
            
                link |
                
                 I don't necessarily have to be paying attention
             
            
                link |
                
                 to exactly what the contact of my fingers with the ball
             
            
                link |
                
                 or some random feature,
             
            
                link |
                
                 like whether or not I'm bending my knees or not.
             
            
                link |
                
                 The key is to try a number of different parameters
             
            
                link |
                
                 until I start to approximate the behavior
             
            
                link |
                
                 that I want to get a little bit better
             
            
                link |
                
                 and then trying to get consistent about that.
             
            
                link |
                
                 Now, many of you involved in sports learning will say,
             
            
                link |
                
                 okay, well, that's obvious, it's just incremental learning.
             
            
                link |
                
                 But the key thing is in those errors.
             
            
                link |
                
                 By isolating the errors and making a number of errors
             
            
                link |
                
                 in a particular aspect of the motor movement,
             
            
                link |
                
                 it signals to the brain that it's plastic.
             
            
                link |
                
                 And if I leave that episode of going
             
            
                link |
                
                 and trying to learn how to shoot free throws,
             
            
                link |
                
                 my brain is still plastic.
             
            
                link |
                
                 Plasticity is a state of the brain and nervous system.
             
            
                link |
                
                 It's not just geared toward the specific thing
             
            
                link |
                
                 I'm trying to learn.
             
            
                link |
                
                 So there are two aspects to plasticity
             
            
                link |
                
                 that I think we really need to highlight.
             
            
                link |
                
                 One is that there's plasticity geared toward the thing
             
            
                link |
                
                 that you are trying to learn specifically.
             
            
                link |
                
                 And then there are states of mind and body
             
            
                link |
                
                 that allow us to access plasticity.
             
            
                link |
                
                 Now, toward the end of this episode,
             
            
                link |
                
                 I'm going to spell out specific protocols
             
            
                link |
                
                 in a little more detail.
             
            
                link |
                
                 That free throw example might not correlate
             
            
                link |
                
                 with what you want to learn.
             
            
                link |
                
                 Actually, I don't have a huge desire to learn free throws.
             
            
                link |
                
                 I've more or less given up on basketball
             
            
                link |
                
                 and free throws in particular.
             
            
                link |
                
                 But I think that it's important to understand
             
            
                link |
                
                 that motor movements are the most straightforward way
             
            
                link |
                
                 to access states of plasticity.
             
            
                link |
                
                 And that can be for sake of learning the motor movement
             
            
                link |
                
                 or for sake of accessing plasticity more generally.
             
            
                link |
                
                 One very important aspect to getting plasticity as an adult
             
            
                link |
                
                 is not just smaller increments, meaning shorter bouts.
             
            
                link |
                
                 So I gave an example of another 100 free throws or something
             
            
                link |
                
                 but going out there and just getting my 10,000 free throws
             
            
                link |
                
                 all at once or packing as much as I can into one episode
             
            
                link |
                
                 is not going to be as efficient for me
             
            
                link |
                
                 as shorter bouts of intense learning as an adult.
             
            
                link |
                
                 Because the error signals are not as well defined.
             
            
                link |
                
                 To my nervous system,
             
            
                link |
                
                 it's not going to know what needs to change.
             
            
                link |
                
                 And so this is really the key element
             
            
                link |
                
                 of incremental learning,
             
            
                link |
                
                 is that you're trying to signal to the nervous system
             
            
                link |
                
                 at least one component that needs to change.
             
            
                link |
                
                 The nervous system needs to know what the error is.
             
            
                link |
                
                 Now, when I shoot free throws, Lord knows,
             
            
                link |
                
                 there are a lot of different kinds of errors that happen.
             
            
                link |
                
                 Probably the way I'm bending my knees, the arc of the ball,
             
            
                link |
                
                 the way I'm organizing my shoulder
             
            
                link |
                
                 is probably where my eyes are, lots of things.
             
            
                link |
                
                 So which ones to focus on.
             
            
                link |
                
                 And that's what I said before,
             
            
                link |
                
                 the beauty of the motor system is
             
            
                link |
                
                 I don't have to worry about all of that.
             
            
                link |
                
                 I just need to get the reps in a number of times
             
            
                link |
                
                 and the nervous system will figure out
             
            
                link |
                
                 how far off my motor commands are
             
            
                link |
                
                 at the level of these maps that I described earlier,
             
            
                link |
                
                 how far those deviate from the desired behavior,
             
            
                link |
                
                 getting the ball into the basket.
             
            
                link |
                
                 And it will start making adjustments.
             
            
                link |
                
                 But as I make adjustments,
             
            
                link |
                
                 or as my nervous system makes adjustments for me,
             
            
                link |
                
                 the key thing is to not start adding a variety of new errors
             
            
                link |
                
                 because then it gets confused.
             
            
                link |
                
                 And so this is why short learning bouts
             
            
                link |
                
                 are absolutely essential.
             
            
                link |
                
                 So let's say it's for learning an instrument as an adult,
             
            
                link |
                
                 probably anywhere from seven minutes to 30 minutes
             
            
                link |
                
                 provided that you're fully attending, you're very focused,
             
            
                link |
                
                 is going to be a pretty significant stimulus
             
            
                link |
                
                 to inspire plasticity in the nervous system.
             
            
                link |
                
                 Now, there is one way to get a lot of plasticity
             
            
                link |
                
                 all at once as an adult.
             
            
                link |
                
                 There is that kind of holy grail thing
             
            
                link |
                
                 of getting massive plasticity
             
            
                link |
                
                 as you would when you were a young person, but as an adult.
             
            
                link |
                
                 And the Knudsen lab revealed this
             
            
                link |
                
                 by setting a very serious contingency on the learning.
             
            
                link |
                
                 What they did was they had a situation
             
            
                link |
                
                 where subjects had to find food
             
            
                link |
                
                 that was displaced in their visual world,
             
            
                link |
                
                 again, by putting prisms,
             
            
                link |
                
                 and they had to find the food and the food made a noise.
             
            
                link |
                
                 There was a noise set kind of the location of the food
             
            
                link |
                
                 through an array of speakers.
             
            
                link |
                
                 Basically, what they found was that
             
            
                link |
                
                 if people have to adjust their visual world
             
            
                link |
                
                 in order to get food, the plasticity would eventually occur,
             
            
                link |
                
                 but it was very slow as an adult.
             
            
                link |
                
                 It was very, very slow.
             
            
                link |
                
                 Unless they actually had to hunt that food.
             
            
                link |
                
                 They actually, in order to eat at all,
             
            
                link |
                
                 they needed plasticity.
             
            
                link |
                
                 And then what happened was remarkable.
             
            
                link |
                
                 What they observed is that the plasticity as an adult
             
            
                link |
                
                 can be as dramatic, as robust as it is in a young person
             
            
                link |
                
                 or in a young animal subject,
             
            
                link |
                
                 provided that there's a serious incentive
             
            
                link |
                
                 for the plasticity to occur.
             
            
                link |
                
                 And this is absolutely important to understand,
             
            
                link |
                
                 which is that how badly we need or want the plasticity
             
            
                link |
                
                 determines how fast that plasticity will arrive,
             
            
                link |
                
                 which is incredible because the brain is just neurons
             
            
                link |
                
                 and soup of chemicals.
             
            
                link |
                
                 So with this, but this means that the importance of something
             
            
                link |
                
                 how important something is to us
             
            
                link |
                
                 actually gates the rate of plasticity
             
            
                link |
                
                 and the magnitude of plasticity.
             
            
                link |
                
                 And this is why just passively going through most things,
             
            
                link |
                
                 going through the motions, as we say,
             
            
                link |
                
                 or just getting our reps in quote unquote
             
            
                link |
                
                 is not sufficient to get the nervous system to change.
             
            
                link |
                
                 This study, a beautiful study
             
            
                link |
                
                 published in the Journal of Neuroscience shows
             
            
                link |
                
                 that if we actually have to accomplish something
             
            
                link |
                
                 in order to eat or in order to get our ration of income,
             
            
                link |
                
                 we will reshape our nervous system very, very quickly.
             
            
                link |
                
                 So the nervous system has a capacity to change
             
            
                link |
                
                 at a tremendous rate to an enormous degree
             
            
                link |
                
                 at any stage of life,
             
            
                link |
                
                 provided it's important enough that that happened.
             
            
                link |
                
                 And I think some of you might be saying,
             
            
                link |
                
                 well, duh, that's obvious.
             
            
                link |
                
                 If it's really crucial,
             
            
                link |
                
                 then of course it's gonna change faster,
             
            
                link |
                
                 but it didn't have to be that way.
             
            
                link |
                
                 And for most people who are trying to learn
             
            
                link |
                
                 how to learn faster or learn better,
             
            
                link |
                
                 they probably, in most cases,
             
            
                link |
                
                 they are hitting a limit
             
            
                link |
                
                 because the need to change is not crucial enough.
             
            
                link |
                
                 And I think there are a number of places
             
            
                link |
                
                 where this has an important relevance
             
            
                link |
                
                 in the people who are battling addiction, for instance.
             
            
                link |
                
                 I will be the first to say that I sympathize with the fact
             
            
                link |
                
                 that addictions have a biological component.
             
            
                link |
                
                 There's clearly cases where people struggle tremendously
             
            
                link |
                
                 to change their behavior and their nervous system,
             
            
                link |
                
                 in some cases, is so disrupted
             
            
                link |
                
                 by whatever substance they've been abusing
             
            
                link |
                
                 or behavior that they've been engaging in
             
            
                link |
                
                 that it's that much harder for them to change.
             
            
                link |
                
                 But we've also seen incredible examples
             
            
                link |
                
                 where when people have to change from an internal standpoint
             
            
                link |
                
                 from their own belief and desire to change,
             
            
                link |
                
                 that massive change is possible.
             
            
                link |
                
                 And so I think that the studies that Knudsen did
             
            
                link |
                
                 showing that incremental learning
             
            
                link |
                
                 can create a huge degree of plasticity as an adult,
             
            
                link |
                
                 as well as when the contingency is very high,
             
            
                link |
                
                 meaning we need to eat or we need to make an income
             
            
                link |
                
                 or we need to do something that's vitally important for us,
             
            
                link |
                
                 that plasticity can happen in these enormous leaps
             
            
                link |
                
                 just like they can in adolescence and young adulthood.
             
            
                link |
                
                 That points to the fact
             
            
                link |
                
                 that it has to be a neurochemical system.
             
            
                link |
                
                 There has to be an underlying mechanism, right?
             
            
                link |
                
                 This wasn't a case of sticking a wire into the brain
             
            
                link |
                
                 or taking a particular drug.
             
            
                link |
                
                 All the chemicals that we're about to talk about
             
            
                link |
                
                 are released from drug stores, if you will,
             
            
                link |
                
                 chemical stores that already reside in all of our brains.
             
            
                link |
                
                 And the key is how to tap into those stores.
             
            
                link |
                
                 And so we're going to next talk about
             
            
                link |
                
                 what are the specific behaviors
             
            
                link |
                
                 that liberate particular categories of chemicals
             
            
                link |
                
                 that allow us to make the most of incremental learning
             
            
                link |
                
                 and that set the stage for plasticity
             
            
                link |
                
                 that is similar enough
             
            
                link |
                
                 or mimics these high contingency states
             
            
                link |
                
                 like the need to get food
             
            
                link |
                
                 or really create a sense of internal urgency,
             
            
                link |
                
                 chemical urgency, if you will.
             
            
                link |
                
                 If you've heard previous episodes of this podcast,
             
            
                link |
                
                 you may have heard me talk about ultradian rhythms,
             
            
                link |
                
                 which are these 90 minute rhythms
             
            
                link |
                
                 that break up our 24 hour day.
             
            
                link |
                
                 They help break up our sleep into different cycles of sleep
             
            
                link |
                
                 like REM sleep and non-REM sleep.
             
            
                link |
                
                 And in waking states, they help us,
             
            
                link |
                
                 or I should say they break up our day in ways
             
            
                link |
                
                 that allow us to learn best
             
            
                link |
                
                 within 90 minute cycles, et cetera.
             
            
                link |
                
                 So some of you might be saying,
             
            
                link |
                
                 wait, you've been talking about ultradian cycles
             
            
                link |
                
                 and a moment ago you were talking about
             
            
                link |
                
                 seven minute or 12 minute or 30 minute learning cycles.
             
            
                link |
                
                 Today we're really talking about
             
            
                link |
                
                 how to tap into plasticity
             
            
                link |
                
                 through the completion of a task
             
            
                link |
                
                 or working towards something repetitively and making errors.
             
            
                link |
                
                 And so just to frame this
             
            
                link |
                
                 in the context of the ultradian cycle,
             
            
                link |
                
                 you might sit down,
             
            
                link |
                
                 decide that you're going to learn a conversational French,
             
            
                link |
                
                 which would mean that you probably
             
            
                link |
                
                 don't already speak French.
             
            
                link |
                
                 So you're going to sit down,
             
            
                link |
                
                 you're going to decide,
             
            
                link |
                
                 you're going to learn some nouns and some verbs.
             
            
                link |
                
                 You might do some practice sets.
             
            
                link |
                
                 The ultradian cycle says that
             
            
                link |
                
                 for the first five to 10 minutes of doing that,
             
            
                link |
                
                 your mind is going to drift
             
            
                link |
                
                 and your focus will probably kick in
             
            
                link |
                
                 provided that you're restricting your visual world
             
            
                link |
                
                 to just the material in front of you,
             
            
                link |
                
                 something we talked about last episode,
             
            
                link |
                
                 somewhere around the 10 or 15 minute mark.
             
            
            
                link |
                
                 you're probably going to get about an hour
             
            
                link |
                
                 of deliberate kind of tunnel vision learning in there.
             
            
                link |
                
                 Your mind will drift.
             
            
                link |
                
                 And then toward the end of that,
             
            
                link |
                
                 what is now an hour and 10 or hour and 20 minute cycle,
             
            
            
                link |
                
                 your brain will start to flicker in and out.
             
            
                link |
                
                 You might start thinking about what you need to eat
             
            
                link |
                
                 or the fact that you have to use the bathroom or something.
             
            
                link |
                
                 And then by the 90 minutes,
             
            
                link |
                
                 it's probably time to just stop the learning bout
             
            
                link |
                
                 and go do something else,
             
            
                link |
                
                 maybe return for a second learning bout later,
             
            
                link |
                
                 but maybe take a nap afterwards
             
            
                link |
                
                 or something to enhance the learning,
             
            
                link |
                
                 but that it's going to happen within
             
            
                link |
                
                 about a 90 minute block,
             
            
                link |
                
                 you're going to go through that cycle of learning.
             
            
                link |
                
                 But when I refer to the seven or 12 or 30 minutes
             
            
            
                link |
                
                 what I mean is when you're really in a mode
             
            
                link |
                
                 of repeating errors, not deliberately,
             
            
                link |
                
                 you're trying your best to accomplish something
             
            
                link |
                
                 and you're failing.
             
            
                link |
                
                 You're absolutely failing.
             
            
                link |
                
                 You're trying to remember, say, the sign language alphabet.
             
            
                link |
                
                 I was trying to teach myself this recently,
             
            
                link |
                
                 and then I keep repeating and repeating,
             
            
                link |
                
                 and then you get to a certain point
             
            
                link |
                
                 where I kept making errors,
             
            
                link |
                
                 making errors, making errors.
             
            
                link |
                
                 You want to keep making errors for this period of time
             
            
                link |
                
                 that I'm saying will last anywhere
             
            
                link |
                
                 for about seven to 30 minutes.
             
            
                link |
                
                 It is exceedingly frustrating,
             
            
                link |
                
                 but that frustration, it liberates the chemical cues
             
            
                link |
                
                 that signal that plasticity needs to happen.
             
            
                link |
                
                 And they also signal the particular neurons that are active.
             
            
                link |
                
                 So in the case of sign language,
             
            
                link |
                
                 it might be the ones that control my hand movements
             
            
                link |
                
                 as well as me thinking about what the different letters are.
             
            
                link |
                
                 It's signaling different components within the networks
             
            
                link |
                
                 of between the brain and body.
             
            
                link |
                
                 And it's trying to figure out,
             
            
                link |
                
                 wait, where are these errors coming from?
             
            
                link |
                
                 Where are the errors coming from?
             
            
                link |
                
                 Ah, it's those neurons.
             
            
                link |
                
                 They're making the mistakes.
             
            
                link |
                
                 They're making the mistakes.
             
            
                link |
                
                 They're making the mistakes.
             
            
                link |
                
                 And it essentially highlights that pathway for change.
             
            
                link |
                
                 And it is the case that when we come back a day or two later
             
            
                link |
                
                 in a learning bout after a nap or a night or two
             
            
                link |
                
                 of deep rest, then what we find is that
             
            
                link |
                
                 we can remember certain things and the motor pathways work.
             
            
                link |
                
                 And we don't always get it perfectly,
             
            
                link |
                
                 but we get a lot of it right whereas we got it wrong before.
             
            
                link |
                
                 So that seven to 30 minute intense learning bout
             
            
                link |
                
                 is within the ultradian cycle.
             
            
                link |
                
                 And I want to be clear about that.
             
            
                link |
                
                 And some people can tolerate many of these per day.
             
            
                link |
                
                 Most people can only tolerate one or two, maybe three.
             
            
                link |
                
                 This is intense work.
             
            
                link |
                
                 If, you know, shooting free throws,
             
            
                link |
                
                 you could probably do it all day.
             
            
                link |
                
                 But what I'm talking about is really trying
             
            
                link |
                
                 to accelerate plasticity by having a period
             
            
                link |
                
                 of the seven to 30 minutes per learning bout
             
            
                link |
                
                 that is specifically about making errors.
             
            
                link |
                
                 I want to really underscore that.
             
            
                link |
                
                 And it's not about, as I mentioned before,
             
            
                link |
                
                 coming up with some little hack or trick
             
            
                link |
                
                 or something of that sort.
             
            
                link |
                
                 It's really about trying to cue the nervous system
             
            
                link |
                
                 that something needs to change
             
            
                link |
                
                 because otherwise it simply won't change.
             
            
                link |
                
                 Now, there's another aspect to learning.
             
            
                link |
                
                 I think it's only fair to mention,
             
            
                link |
                
                 which is that we can all learn very easily
             
            
                link |
                
                 when there's something very bad happens to us.
             
            
                link |
                
                 And I don't wish this on anyone,
             
            
                link |
                
                 but it is the case that if something really terrible happens
             
            
                link |
                
                 that we will have a lifetime memory for that event.
             
            
                link |
                
                 There are processes that allow us to uncouple
             
            
                link |
                
                 the emotional load of that event.
             
            
                link |
                
                 I talked about some of those a few episodes back,
             
            
                link |
                
                 the episode on dreams, trauma, and hallucinations.
             
            
                link |
                
                 And we're going to return to trauma release, PTSD,
             
            
                link |
                
                 and some of those other themes in a future episode.
             
            
                link |
                
                 But the reason why negative experiences
             
            
                link |
                
                 can be wired into us so quickly
             
            
                link |
                
                 is because our nervous system's main job is to keep us safe.
             
            
                link |
                
                 But at a deeper level, it's because negative experiences
             
            
                link |
                
                 cue us to the fact that whatever's happening
             
            
                link |
                
                 that's really bad is very different
             
            
                link |
                
                 than the other things that tend to happen before.
             
            
                link |
                
                 So most of our experience doesn't remap us,
             
            
                link |
                
                 but those negative experiences
             
            
                link |
                
                 deploy high levels of norepinephrine,
             
            
                link |
                
                 high levels of acetylcholine, and really make,
             
            
                link |
                
                 so that whatever it is that we experience
             
            
                link |
                
                 in that bad episode is essentially cued up.
             
            
                link |
                
                 And so we're on the lookout for it.
             
            
                link |
                
                 And this has a number of negative effects,
             
            
                link |
                
                 but in terms of psychological and emotional effects,
             
            
                link |
                
                 but it is really a process designed to keep us safe.
             
            
                link |
                
                 The other ways in which we can learn more quickly
             
            
                link |
                
                 besides just making errors
             
            
                link |
                
                 is when something really surprises us.
             
            
                link |
                
                 And if we're positively surprised by something,
             
            
                link |
                
                 or we are just flooded with this molecule dopamine,
             
            
                link |
                
                 then there's a great opportunity for plasticity.
             
            
                link |
                
                 Dopamine is a molecule
             
            
                link |
                
                 that's almost always associated with pleasure
             
            
                link |
                
                 and with the accomplishment of a particular goal,
             
            
                link |
                
                 but it's really also a molecule of motivation.
             
            
                link |
                
                 It's a molecule that is released inside of us
             
            
                link |
                
                 when we think we're on the right path.
             
            
                link |
                
                 And it does have a capacity to increase neuroplasticity,
             
            
                link |
                
                 motivation, et cetera, it's released in response
             
            
                link |
                
                 to a number of natural behaviors,
             
            
                link |
                
                 just that help with the progression of ours
             
            
                link |
                
                 and other species, things like food, sex,
             
            
                link |
                
                 in some sense, social connection,
             
            
                link |
                
                 although that's more serotonin,
             
            
                link |
                
                 and serotonin doesn't have the same effects on plasticity,
             
            
                link |
                
                 quite the same, and we'll talk about a few later.
             
            
                link |
                
                 But dopamine is when we think we're on the right path
             
            
                link |
                
                 toward an external goal, a little bit is released,
             
            
                link |
                
                 and it tends to give us more motivation toward that goal.
             
            
                link |
                
                 I think everyone could stand to enhance the rate of learning
             
            
                link |
                
                 by doing the following.
             
            
                link |
                
                 Learn to attach dopamine in a subjective way
             
            
                link |
                
                 to this process of making errors,
             
            
                link |
                
                 because that's really combining two modes of plasticity
             
            
                link |
                
                 in ways that together can accelerate the plasticity.
             
            
                link |
                
                 So earlier I talked about making errors
             
            
                link |
                
                 and having a focus bout of learning
             
            
                link |
                
                 that includes making a lot of errors
             
            
                link |
                
                 inside of that learning bout,
             
            
                link |
                
                 that is going to be frustrating,
             
            
                link |
                
                 but the frustration itself is the cue,
             
            
                link |
                
                 and epinephrine will be very high under those conditions,
             
            
                link |
                
                 but if you can just subjectively associate that experience
             
            
                link |
                
                 with something good and that you want to continue
             
            
                link |
                
                 down that path as opposed to quitting
             
            
                link |
                
                 when you hit the point of frustration,
             
            
                link |
                
                 well, then you now start to create a synergy
             
            
                link |
                
                 between the dopamine that's released
             
            
                link |
                
                 when we subjectively think something is good
             
            
                link |
                
                 or tell ourselves something is good,
             
            
                link |
                
                 and that situation of making failures.
             
            
                link |
                
                 In other words, making failing repetitively,
             
            
                link |
                
                 provided we're engaged in a very specific set of behaviors
             
            
                link |
                
                 when we do it, as well as telling ourselves
             
            
                link |
                
                 that those failures are good for learning and good for us,
             
            
                link |
                
                 creates an outsized effect on the rate of plasticity.
             
            
                link |
                
                 It accelerates plasticity.
             
            
                link |
                
                 Now, some of you might be asking, and I get asked a lot,
             
            
                link |
                
                 well, how do I get dopamine to be released?
             
            
                link |
                
                 Can I just tell myself that something is good
             
            
            
                link |
                
                 Well, actually, yes, believe it or not.
             
            
                link |
                
                 The thing about dopamine is it's highly subjective.
             
            
                link |
                
                 What's funny to one person
             
            
                link |
                
                 is not necessarily funny to the next,
             
            
                link |
                
                 so it has to have some sense of authenticity for you,
             
            
                link |
                
                 but if you really want to be learning the thing
             
            
                link |
                
                 that you're trying to learn,
             
            
                link |
                
                 that should be reason enough to tell yourself,
             
            
                link |
                
                 well, I'm frustrated,
             
            
                link |
                
                 but the frustration is the source of accelerated learning.
             
            
                link |
                
                 Dopamine is one of these incredible molecules
             
            
                link |
                
                 that both can be released according to things
             
            
                link |
                
                 that are hardwired in us to release dopamine.
             
            
                link |
                
                 Again, things like food, sex, warmth when we're cold,
             
            
                link |
                
                 cool environments when we're too warm.
             
            
                link |
                
                 It's that kind of pleasure molecule overall,
             
            
                link |
                
                 but it's also highly subjective
             
            
                link |
                
                 what releases dopamine in one person versus the next.
             
            
                link |
                
                 So everyone releases dopamine
             
            
                link |
                
                 in response to those very basic kind of behaviors
             
            
            
                link |
                
                 but dopamine is also released
             
            
                link |
                
                 according to what we subjectively believe is good for us,
             
            
                link |
                
                 and that's what's so powerful about it.
             
            
                link |
                
                 In fact, a book that I highly recommend
             
            
                link |
                
                 if you want to read more about dopamine
             
            
                link |
                
                 is a book that, frankly, I wish I had written.
             
            
                link |
                
                 It's such a wonderful book.
             
            
                link |
                
                 It's called The Molecule of More,
             
            
                link |
                
                 and it really talks about dopamine
             
            
                link |
                
                 not just as a molecule associated with reward,
             
            
                link |
                
                 but a molecule associated with motivation and pursuit
             
            
                link |
                
                 and just how subjectively controlled dopamine can be.
             
            
                link |
                
                 So make lots of errors.
             
            
                link |
                
                 Tell yourself that those errors are important and good
             
            
                link |
                
                 for your overall learning goals.
             
            
                link |
                
                 So learn to attach dopamine,
             
            
                link |
                
                 meaning release dopamine in your brain
             
            
                link |
                
                 when you start to make errors.
             
            
                link |
                
                 Keep the bouts of learning relatively short
             
            
                link |
                
                 if you're an adult.
             
            
                link |
                
                 Younger people can probably engage
             
            
                link |
                
                 in more bouts of learning,
             
            
                link |
                
                 and it's probably one of the reasons
             
            
                link |
                
                 why they learn so much faster.
             
            
                link |
                
                 They can just pack so much more information
             
            
                link |
                
                 into the brains and nervous systems compared to adults.
             
            
                link |
                
                 You know, it's a little bit like, I'll use the example
             
            
                link |
                
                 of performance-enhancing drugs.
             
            
                link |
                
                 You know, some of those drugs
             
            
                link |
                
                 probably do enhance performance
             
            
                link |
                
                 at the level of increasing red blood cell count, et cetera,
             
            
                link |
                
                 but a lot of what those drugs do
             
            
                link |
                
                 is they allow athletes to recover faster
             
            
                link |
                
                 so they can just train more.
             
            
                link |
                
                 They allow them to do more work.
             
            
                link |
                
                 And so being a child is a little bit
             
            
                link |
                
                 like being in a performance-enhanced brain milieu.
             
            
                link |
                
                 Their brains are kind of unnatural, healthy neurochemicals
             
            
                link |
                
                 that afford them a lot more learning should they pursue it.
             
            
                link |
                
                 So this goes back to my advice for young people early on.
             
            
                link |
                
                 If you're young, what should you do?
             
            
                link |
                
                 Learn as much as you can
             
            
                link |
                
                 about as many things as you possibly can.
             
            
                link |
                
                 And I suggest specializing in something.
             
            
                link |
                
                 I guess I'm not in a position to give anyone direct advice,
             
            
                link |
                
                 but I would say hopefully by about age 30,
             
            
                link |
                
                 hopefully younger, you have some sense of what excites you
             
            
                link |
                
                 and try and get really good at that thing
             
            
                link |
                
                 provided it serves the world for better.
             
            
                link |
                
                 But that's all I'll say in terms of parenting advice.
             
            
                link |
                
                 It's not my place, but maybe sometime I'll have an episode
             
            
                link |
                
                 completely devoted to sort of youth and learning in youth.
             
            
                link |
                
                 But once you're attaching dopamine
             
            
                link |
                
                 to this process of making errors,
             
            
                link |
                
                 then I start getting lots of questions
             
            
                link |
                
                 that really are the right questions,
             
            
                link |
                
                 which are, you know, how often should I do this?
             
            
                link |
                
                 And when should I be doing this?
             
            
            
                link |
                
                 Well, I've talked a little bit about this
             
            
                link |
                
                 in previous episodes, but as long as we're now
             
            
                link |
                
                 kind of into the nitty gritty of tools and application,
             
            
                link |
                
                 each of us have some natural times throughout the day
             
            
                link |
                
                 when we are going to be much better
             
            
                link |
                
                 at tolerating these errors and much more focused
             
            
                link |
                
                 on what it is that we're trying to do.
             
            
                link |
                
                 Last episode was about focus,
             
            
                link |
                
                 but chances are that you can't focus as well at 4 p.m.
             
            
                link |
                
                 as you can at 10 a.m.
             
            
                link |
                
                 It differs for everybody depending on when you're sleeping
             
            
                link |
                
                 and your kind of natural chemistry and rhythms.
             
            
                link |
                
                 But find the time or times of day
             
            
                link |
                
                 when you naturally have the highest mental acuity.
             
            
                link |
                
                 And that's really when you want to engage
             
            
                link |
                
                 in these learning bouts.
             
            
                link |
                
                 And then get to the point where you're making errors
             
            
                link |
                
                 and then keep making errors for seven to 30 minutes.
             
            
                link |
                
                 Just keep making those errors and drill through it.
             
            
                link |
                
                 And you're almost seeking frustration.
             
            
                link |
                
                 And if you can find some pleasure in the frustration,
             
            
                link |
                
                 yes, that is a state that exists.
             
            
                link |
                
                 You have created the optimal neurochemical milieu
             
            
                link |
                
                 for learning that thing.
             
            
                link |
                
                 But then here's the beauty of it.
             
            
                link |
                
                 You also created the optimal milieu
             
            
                link |
                
                 for learning other things afterward.
             
            
                link |
                
                 If you leave that bout of,
             
            
                link |
                
                 I give the example of free throws,
             
            
                link |
                
                 or maybe it's playing tennis,
             
            
                link |
                
                 or maybe it's some other skill,
             
            
                link |
                
                 and you sit down to read a book,
             
            
                link |
                
                 your brain is in a heightened state
             
            
                link |
                
                 to learn and retain the information.
             
            
                link |
                
                 Because those chemicals don't get released
             
            
                link |
                
                 and then shut down.
             
            
                link |
                
                 You're creating a whole milieu,
             
            
                link |
                
                 an environment of these chemicals.
             
            
                link |
                
                 And the tale of how long these chemicals stay
             
            
                link |
                
                 sloshing around in your brain has too many factors
             
            
                link |
                
                 for me to put a hard number on it.
             
            
                link |
                
                 It's going to depend on transporters and enzymes
             
            
                link |
                
                 and all sorts of things.
             
            
                link |
                
                 But at least for an hour or so, I would say,
             
            
                link |
                
                 you're going to be in a state of heightened learning
             
            
                link |
                
                 and the ability to learn, not just the motor patterns,
             
            
                link |
                
                 but cognitive information, language information.
             
            
                link |
                
                 Maybe you go to therapy right after that
             
            
                link |
                
                 and you work on something in a very deliberate way
             
            
                link |
                
                 that you're trying to work on.
             
            
                link |
                
                 Maybe you don't go to therapy.
             
            
                link |
                
                 Maybe you do something else that's important to you.
             
            
                link |
                
                 Again, there are just a variety of examples I could give.
             
            
                link |
                
                 There are a number of things that allow us
             
            
                link |
                
                 to powerfully access the states of error
             
            
                link |
                
                 that are kind of surprising, but also kind of fun.
             
            
                link |
                
                 And these aren't, again, these aren't gimmicks.
             
            
                link |
                
                 These tap into these basic mechanisms of plasticity.
             
            
                link |
                
                 And the three that I'd like to talk about next
             
            
                link |
                
                 are balance, meaning the vestibular system,
             
            
                link |
                
                 as well as the two sides of what I call limbic friction
             
            
                link |
                
                 or autonomic arousal.
             
            
                link |
                
                 And if none of that makes sense,
             
            
                link |
                
                 I'm going to put a fine point on each one of those
             
            
                link |
                
                 and what it is and why it works
             
            
                link |
                
                 for opening up neuroplasticity.
             
            
                link |
                
                 Let's talk about limbic friction.
             
            
                link |
                
                 Now, limbic friction is not a term
             
            
                link |
                
                 you're going to find in the textbooks.
             
            
                link |
                
                 So if any of my colleagues are listening,
             
            
                link |
                
                 I want to repeat limbic friction.
             
            
                link |
                
                 I realize it's not something you're going to find
             
            
                link |
                
                 in any of the textbooks.
             
            
                link |
                
                 But it is an important principle
             
            
                link |
                
                 that captures a lot of information that is in textbooks,
             
            
                link |
                
                 both neurobiology and psychology,
             
            
                link |
                
                 and it has some really important implications.
             
            
                link |
                
                 Limbic friction is my attempt to give a name to something
             
            
                link |
                
                 that is more nuanced and mechanistic than stress.
             
            
                link |
                
                 Because typically when we hear about stress,
             
            
                link |
                
                 we think of heartbeat going too fast, breathing too fast,
             
            
                link |
                
                 sweating, and not being in a state that we want.
             
            
                link |
                
                 We're too alert and we want to be more calm.
             
            
                link |
                
                 And indeed, that's one condition
             
            
                link |
                
                 in which we have limbic friction,
             
            
                link |
                
                 meaning our limbic system is taking control
             
            
                link |
                
                 of a number of different aspects of our autonomic
             
            
                link |
                
                 or automatic biology.
             
            
                link |
                
                 And we are struggling to control that
             
            
                link |
                
                 through what we call top-down mechanisms.
             
            
                link |
                
                 We're trying to calm down in order to reduce
             
            
                link |
                
                 that level of arousal.
             
            
                link |
                
                 We're all familiar with this.
             
            
                link |
                
                 It's called the stress response.
             
            
                link |
                
                 However, there's another aspect of stress
             
            
                link |
                
                 that's just as important, which is when we're tired
             
            
                link |
                
                 and we're fatigued and we need to engage,
             
            
                link |
                
                 we need to be more alert than we are.
             
            
                link |
                
                 And so what I call limbic friction
             
            
                link |
                
                 is really designed to describe the fact
             
            
                link |
                
                 that when our autonomic nervous system
             
            
                link |
                
                 isn't where we want it,
             
            
                link |
                
                 meaning we're trying to be more alert
             
            
                link |
                
                 or we're trying to be less alert,
             
            
                link |
                
                 both of those feel stressful to people.
             
            
                link |
                
                 So the other way to put it is that the word stress
             
            
                link |
                
                 is not a very good word to describe
             
            
                link |
                
                 what most people experience as stressful
             
            
                link |
                
                 because it can either be being too tired
             
            
                link |
                
                 or being too alert.
             
            
                link |
                
                 Now, why am I bringing this up
             
            
                link |
                
                 in the discussion about neuroplasticity?
             
            
                link |
                
                 This is not a discussion about stress.
             
            
                link |
                
                 At some point, we will talk about stress
             
            
                link |
                
                 and tools to deal with stress.
             
            
                link |
                
                 But the reason I'm bringing this up
             
            
                link |
                
                 is that in order to access neuroplasticity,
             
            
                link |
                
                 you need these components of focus.
             
            
                link |
                
                 You need the component of attaching subjective reward.
             
            
                link |
                
                 You need to make errors, all this stuff.
             
            
                link |
                
                 And a lot of people find it difficult
             
            
                link |
                
                 to just get into the overall state to access those things.
             
            
                link |
                
                 So now there's a series of gates
             
            
                link |
                
                 that people are having a hard time accessing.
             
            
                link |
                
                 They're too tired and they can't focus, for instance.
             
            
                link |
                
                 Well, here's the beauty of it.
             
            
                link |
                
                 If you are too alert, meaning you're too anxious
             
            
                link |
                
                 and you want to calm down in order to learn better,
             
            
                link |
                
                 there are things that you can do.
             
            
                link |
                
                 The two that I've spoken about previously
             
            
                link |
                
                 on various podcasts,
             
            
                link |
                
                 and I'll just review them really quickly,
             
            
                link |
                
                 are the double inhale-exhale.
             
            
                link |
                
                 So inhaling twice through the nose
             
            
                link |
                
                 and exhaling once through the mouth.
             
            
                link |
                
                 This is not some yogic trick or some hack.
             
            
                link |
                
                 This is what's called a physiological psi.
             
            
                link |
                
                 It offloads carbon dioxide from the lungs.
             
            
                link |
                
                 It has a number of different effects.
             
            
                link |
                
                 These were described in textbooks
             
            
                link |
                
                 and dating back to the 30s.
             
            
                link |
                
                 And a number of laboratories have explored
             
            
                link |
                
                 the neural circuitry underlying
             
            
                link |
                
                 these so-called physiological psi.
             
            
                link |
                
                 That will calm you down faster than anything else
             
            
                link |
                
                 that I'm aware of.
             
            
                link |
                
                 The other thing is starting to remove your tunnel vision.
             
            
                link |
                
                 When you use tunnel vision, you're very focused.
             
            
                link |
                
                 That epinephrine is released by dilating your field of gaze,
             
            
                link |
                
                 so-called panoramic vision.
             
            
            
                link |
                
                 So now you can start to sort of move up and down
             
            
                link |
                
                 this level of autonomic arousal.
             
            
                link |
                
                 The key is you want to be in a state of arousal
             
            
                link |
                
                 that's ideally matched to the thing
             
            
                link |
                
                 that you're trying to perform or learn.
             
            
                link |
                
                 So if I'm really anxious
             
            
                link |
                
                 and I can't even pick up the basketball
             
            
                link |
                
                 or I feel like I'm shaking or my muscles are too tight,
             
            
                link |
                
                 I don't have that kind of looseness.
             
            
                link |
                
                 Now when I move like that,
             
            
                link |
                
                 it almost makes it look like I could throw a free throw,
             
            
                link |
                
                 but I miss 95% of the time,
             
            
                link |
                
                 unless the basket is very, very low
             
            
                link |
                
                 and I place it indirectly.
             
            
                link |
                
                 But I guess that's not a free throw, is it?
             
            
                link |
                
                 In any case, the point being that you want to be
             
            
                link |
                
                 in a state of alertness, but calm.
             
            
                link |
                
                 And so you need to have ways to calm yourself down
             
            
                link |
                
                 when you're too amped up.
             
            
                link |
                
                 But the other side of limbic friction is important too.
             
            
                link |
                
                 If you are too tired and you can't focus,
             
            
                link |
                
                 well then it's going to be impossible
             
            
                link |
                
                 to even get to the starting line, so to speak,
             
            
                link |
                
                 for engaging in neuroplasticity
             
            
                link |
                
                 through incremental learning, et cetera.
             
            
            
                link |
                
                 there are other methods that you can do to wake yourself up.
             
            
                link |
                
                 The best thing you should do is get a good night's sleep,
             
            
                link |
                
                 but that's not always possible
             
            
                link |
                
                 or use a NSDR, non-sleep deep rest protocol.
             
            
                link |
                
                 But if you've already done those things
             
            
                link |
                
                 or you're simply exhausted for whatever other reason,
             
            
                link |
                
                 then there are other things that I often get asked about,
             
            
                link |
                
                 like sure, a cup of coffee or super oxygenation breathing,
             
            
                link |
                
                 which means inhaling more than exhaling
             
            
                link |
                
                 on average in a breathing bout.
             
            
                link |
                
                 These are, now we're sort of getting toward the realm
             
            
                link |
                
                 of like how you could trick your nervous system
             
            
            
                link |
                
                 And if you bring more oxygen in
             
            
                link |
                
                 by making your inhales deeper and longer,
             
            
                link |
                
                 you will become more alert.
             
            
                link |
                
                 You'll start to actually deploy norepinephrine
             
            
                link |
                
                 if you breathe very fast.
             
            
                link |
                
                 So there are things that you can do to move up or down
             
            
                link |
                
                 this so-called autonomic arousal arc.
             
            
                link |
                
                 And what you want to ask before you undergo
             
            
                link |
                
                 any learning bout is how much limbic friction
             
            
                link |
                
                 am I experiencing?
             
            
                link |
                
                 Am I too alert and I want to be calmer
             
            
                link |
                
                 or am I too calm and too sleepy
             
            
                link |
                
                 and I want to be more alert?
             
            
                link |
                
                 You're going to need to engage in behaviors
             
            
                link |
                
                 that bring you to the starting line in order to learn.
             
            
                link |
                
                 There are other things that you can do
             
            
                link |
                
                 in order to then learn better and faster
             
            
                link |
                
                 besides incremental learning
             
            
                link |
                
                 and those center on the vestibular system.
             
            
                link |
                
                 And this may come as a surprise to some people,
             
            
                link |
                
                 but probably not as a surprise to some of you
             
            
                link |
                
                 whose professions or whose recreation
             
            
                link |
                
                 involves a lot of motor activity
             
            
                link |
                
                 and sort of what we call high dimensional skill activity,
             
            
                link |
                
                 not just running or cycling
             
            
                link |
                
                 or very linear activities like weightlifting,
             
            
                link |
                
                 but things that involve inversions
             
            
                link |
                
                 and a lot of lateral movement,
             
            
                link |
                
                 actual sports, jumping, diving, rolling,
             
            
                link |
                
                 these kinds of things, gymnastics type stuff.
             
            
                link |
                
                 Why the vestibular system to access neuroplasticity?
             
            
                link |
                
                 Well, we have a hardwired system for balance
             
            
                link |
                
                 and here's how it works in as simple terms
             
            
                link |
                
                 as I can possibly come up with.
             
            
                link |
                
                 As we move through space or even if we're stationary,
             
            
                link |
                
                 there are really three main planes of movement.
             
            
                link |
                
                 Now I realize some people are just listening to this
             
            
                link |
                
                 so I'm going to do this for both the folks
             
            
                link |
                
                 that are just listening
             
            
                link |
                
                 and for those of you that are watching on video.
             
            
                link |
                
                 So there are three main modes of movement
             
            
                link |
                
                 and it turns out that your brain doesn't really know
             
            
                link |
                
                 where your body is except when
             
            
                link |
                
                 through that proprioceptive feedback.
             
            
                link |
                
                 The main way it knows is through three planes of movement
             
            
                link |
                
                 that we call pitch, which is like nodding.
             
            
                link |
                
                 So if I nod like this, that's pitch.
             
            
                link |
                
                 Then there's yaw, which is side to side,
             
            
                link |
                
                 which is like shaking my head, no.
             
            
                link |
                
                 And then there's roll from side to side,
             
            
                link |
                
                 like when a puppy looks at you like, that kind of thing.
             
            
                link |
                
                 So pitch, yaw, and roll.
             
            
                link |
                
                 And the pilots out there will know
             
            
                link |
                
                 exactly what I'm talking about.
             
            
                link |
                
                 The brain knows the orientation and position
             
            
                link |
                
                 of your body relative to gravity,
             
            
                link |
                
                 depending on whether or not your brain and your head
             
            
                link |
                
                 actually is engaging more in pitch, yaw, or roll,
             
            
                link |
                
                 or some combination.
             
            
                link |
                
                 Because if I lean down like so,
             
            
                link |
                
                 or like so, it's a combination of pitch, yaw, and roll.
             
            
                link |
                
                 Now you might say like, what is going on here?
             
            
                link |
                
                 Well, we have these little things in our inner ear
             
            
                link |
                
                 called the semicircular canals.
             
            
                link |
                
                 Just like our eyes have two main functions,
             
            
                link |
                
                 one is to see objects in space,
             
            
                link |
                
                 and the other is to set our circadian clocks
             
            
                link |
                
                 through subconscious mechanisms,
             
            
                link |
                
                 our ears have two main roles.
             
            
                link |
                
                 One is to hear, right, to perceive sound waves
             
            
                link |
                
                 or take in sound waves for perception, so-called hearing.
             
            
                link |
                
                 And the other is balance or vestibular function.
             
            
                link |
                
                 So sitting in our ears are these semicircular canals,
             
            
                link |
                
                 and they're these little tubes where these little stones,
             
            
                link |
                
                 they're actually little bits of calcium,
             
            
                link |
                
                 roll back and forth like little marbles.
             
            
                link |
                
                 When we roll this way, they roll this way.
             
            
                link |
                
                 When we pitch, when we go from side to side,
             
            
                link |
                
                 there's some that sit flat like this,
             
            
                link |
                
                 and they go like marbles inside of a hula hoop.
             
            
                link |
                
                 And then we have roll.
             
            
                link |
                
                 There's some that are kind of at 45 degrees to those,
             
            
                link |
                
                 and it's kind of pitch, yaw, and roll.
             
            
                link |
                
                 So yeah, okay, great.
             
            
                link |
                
                 That sends signals to the rest of our brain and body
             
            
                link |
                
                 that tell us how to compensate
             
            
                link |
                
                 for shifts relative to gravity.
             
            
                link |
                
                 And I say, okay, wait,
             
            
                link |
                
                 I thought we were talking about plasticity,
             
            
                link |
                
                 but this is where it gets really, really cool.
             
            
                link |
                
                 Errors in vestibular motor sensory experience,
             
            
                link |
                
                 meaning when we are off balance and we have to compensate
             
            
                link |
                
                 by looking at, thinking about,
             
            
                link |
                
                 or responding to the world differently,
             
            
                link |
                
                 cause an area of our brain called the cerebellum,
             
            
                link |
                
                 it actually means mini brain,
             
            
                link |
                
                 and it looks like a little mini brain
             
            
                link |
                
                 like tucked below our cortex in the back,
             
            
                link |
                
                 cause the cerebellum to signal
             
            
                link |
                
                 some of these deeper brain centers
             
            
                link |
                
                 that release dopamine, norepinephrine, and acetylcholine.
             
            
                link |
                
                 And that's because these circuits in the inner ear,
             
            
                link |
                
                 et cetera, and the cerebellum,
             
            
                link |
                
                 they were designed to recalibrate our motor movements
             
            
                link |
                
                 when our relationship to gravity changes,
             
            
                link |
                
                 something fundamental to survival.
             
            
                link |
                
                 We can't afford to be falling down all the time
             
            
                link |
                
                 or missing things that we grabbed for,
             
            
                link |
                
                 or running in the wrong direction
             
            
                link |
                
                 when something is pursuing us.
             
            
                link |
                
                 These are hardwired circuits
             
            
                link |
                
                 that tap right into these chemical pathways.
             
            
                link |
                
                 And those chemical pathways are the gates to plasticity.
             
            
                link |
                
                 So I really want to spell this out clearly
             
            
                link |
                
                 cause I've given a lot of information today.
             
            
                link |
                
                 The first thing is how are you arriving
             
            
                link |
                
                 to the learning bout?
             
            
                link |
                
                 You need to make sure your level
             
            
                link |
                
                 of autonomic arousal is correct.
             
            
                link |
                
                 The ideal state is going to be clear, calm, and focused,
             
            
                link |
                
                 maybe a little bit more on the arousal level,
             
            
                link |
                
                 like heightened arousal.
             
            
                link |
                
                 So understand limbic friction,
             
            
                link |
                
                 understand that you can be too tired,
             
            
                link |
                
                 in which case you're going to need
             
            
                link |
                
                 to get yourself a little more alert,
             
            
                link |
                
                 or you can be too alert
             
            
                link |
                
                 and you're going to need to get yourself calmer.
             
            
                link |
                
                 That gets you to the starting line.
             
            
                link |
                
                 When you're at the starting line,
             
            
                link |
                
                 then you're going to go into a learning bout
             
            
                link |
                
                 and that's when you want to start making these errors, okay?
             
            
                link |
                
                 But what I'm saying is there's a layer in between
             
            
                link |
                
                 where if you are interested in using motor patterns
             
            
                link |
                
                 as a way to open up plasticity for all kinds of learning,
             
            
                link |
                
                 not just motor learning,
             
            
                link |
                
                 disrupting your vestibular motor relationship,
             
            
                link |
                
                 meaning, and I'll tell you how to do that in a moment,
             
            
                link |
                
                 can deploy or release neurochemicals in the brain
             
            
                link |
                
                 that place you into a state
             
            
                link |
                
                 that makes you much better at learning
             
            
                link |
                
                 and making errors much more pleasureful.
             
            
                link |
                
                 You're much more willing to do that.
             
            
                link |
                
                 Now, some of you are probably saying flow state, flow state.
             
            
                link |
                
                 Okay, I have friends that work on flow states
             
            
                link |
                
                 and who are involved in flow states
             
            
                link |
                
                 and trying to figure out what they are.
             
            
                link |
                
                 I have great respect for those people.
             
            
                link |
                
                 So I want to tip my hat to them, very important work.
             
            
                link |
                
                 But again, flow is an expression
             
            
                link |
                
                 of what you already know how to do.
             
            
                link |
                
                 It's not how you learn,
             
            
                link |
                
                 it's how you express what you've already learned.
             
            
                link |
                
                 So I want to be really clear about that.
             
            
                link |
                
                 It's been kind of presented as this super state
             
            
                link |
                
                 or highly desirable state,
             
            
                link |
                
                 but it's that we can all reach for.
             
            
                link |
                
                 That's the wrong rung to reach for
             
            
                link |
                
                 until you already know how to do the things
             
            
                link |
                
                 that I'm describing, in my opinion.
             
            
                link |
                
                 So the vestibular system,
             
            
                link |
                
                 if you can engage the vestibular system
             
            
                link |
                
                 and create some errors within the vestibular motor operations
             
            
                link |
                
                 that you're carrying out,
             
            
                link |
                
                 you create a neurochemical state
             
            
                link |
                
                 that then makes you very, very good
             
            
                link |
                
                 at learning very quickly.
             
            
                link |
                
                 Regardless of age.
             
            
                link |
                
                 So what would this look like?
             
            
                link |
                
                 Does this mean just doing inversions?
             
            
                link |
                
                 Well, does this mean doing yoga?
             
            
            
                link |
                
                 Does this mean taking corners faster on your road bike?
             
            
            
                link |
                
                 let's say you always swim freestyle or breaststroke?
             
            
                link |
                
                 Does this mean swimming backstroke or butterfly?
             
            
            
                link |
                
                 It depends, however,
             
            
                link |
                
                 on a very, very easy to understand parameter,
             
            
                link |
                
                 which is how regularly you perform
             
            
                link |
                
                 a particular motor behavior
             
            
                link |
                
                 and how novel a behavior is.
             
            
                link |
                
                 So the more novel that a behavior is
             
            
                link |
                
                 in terms of your relationship to gravity,
             
            
                link |
                
                 the more it will open up the opportunity for plasticity.
             
            
                link |
                
                 Have you ever seen somebody
             
            
                link |
                
                 who just jumped out of the plane for the first time
             
            
            
                link |
                
                 I don't even want to think about what,
             
            
                link |
                
                 if you've just seen somebody who jumped out of a plane
             
            
                link |
                
                 for the first time without a parachute,
             
            
                link |
                
                 I would just hope the plane was on the ground.
             
            
                link |
                
                 But if you've seen somebody after that,
             
            
                link |
                
                 they are in this incredible state
             
            
                link |
                
                 because their body and brain
             
            
                link |
                
                 are flooded with all these neurochemicals
             
            
                link |
                
                 because it's very novel to them.
             
            
                link |
                
                 However, I've got friends from communities
             
            
                link |
                
                 that have done thousands upon thousands,
             
            
                link |
                
                 maybe tens of thousands of jumps,
             
            
                link |
                
                 and they're always alert and aware,
             
            
                link |
                
                 but it becomes pretty regular for them.
             
            
            
                link |
                
                 And they're not in this kind of buzzed out,
             
            
                link |
                
                 excited state afterwards because it's routine for them.
             
            
                link |
                
                 So the key is to bring novelty
             
            
                link |
                
                 to the vestibular motor experience.
             
            
                link |
                
                 The vestibular motor commands that you're performing.
             
            
                link |
                
                 And how do you do that?
             
            
                link |
                
                 Well, it's all about your orientation relative to gravity.
             
            
                link |
                
                 Now, I wouldn't want anyone to place themselves at risk.
             
            
                link |
                
                 So if you can't do handstands,
             
            
                link |
                
                 don't try and do them, freestanding and whatever.
             
            
                link |
                
                 If you're good at handstands,
             
            
                link |
                
                 guess how much plasticity doing a handstands
             
            
                link |
                
                 for half an hour is going to create for you?
             
            
            
            
                link |
                
                 Your body is fully comfortable walking on your hands.
             
            
                link |
                
                 I see these people walking on your hands,
             
            
                link |
                
                 being upside down, being inverted.
             
            
                link |
                
                 Your Cirque du Soleil performers,
             
            
                link |
                
                 they're very comfortable there.
             
            
                link |
                
                 And there's zero learning, zero plasticity
             
            
                link |
                
                 because the failures and errors
             
            
                link |
                
                 and the relationship to gravity
             
            
                link |
                
                 are very typical for that individual.
             
            
                link |
                
                 Now, what this means is
             
            
                link |
                
                 that if we're going to use motor practices
             
            
                link |
                
                 to open up plasticity for learning,
             
            
                link |
                
                 not just those practices,
             
            
                link |
                
                 but maybe some cognitive skills
             
            
                link |
                
                 or other things in the period that follows,
             
            
                link |
                
                 we need to create a sense of novelty relative to gravity.
             
            
                link |
                
                 And that means being either in a new position
             
            
                link |
                
                 or slightly unstable.
             
            
                link |
                
                 Believe it or not, I don't want anyone injuring themselves,
             
            
                link |
                
                 but the sensation of falling or close to falling
             
            
                link |
                
                 signals the cerebellum to signal the deep brain centers
             
            
                link |
                
                 that release these neurochemicals
             
            
                link |
                
                 that something is very different
             
            
                link |
                
                 and we need to correct this error very, very fast.
             
            
                link |
                
                 Earlier, I was talking about high contingencies
             
            
                link |
                
                 for learning and you definitely don't want to make it
             
            
                link |
                
                 to kind of like either survive this or die kind of experience
             
            
                link |
                
                 I confess I occasionally look at these parkour videos
             
            
                link |
                
                 on YouTube and believe it or not,
             
            
                link |
                
                 a lot of those people have died.
             
            
                link |
                
                 The ones that do these ridiculous things
             
            
                link |
                
                 of hanging off of buildings and things,
             
            
                link |
                
                 I am not suggesting you do that, please don't do that.
             
            
                link |
                
                 What I'm talking about is finding safe ways
             
            
                link |
                
                 to explore the sensory motor vestibular space as we call it,
             
            
                link |
                
                 the relationship between those things.
             
            
                link |
                
                 So that could be through yoga.
             
            
                link |
                
                 If you're terrible at yoga,
             
            
                link |
                
                 there's more opportunity for you to learn
             
            
                link |
                
                 than somebody who's very skilled at yoga, for instance,
             
            
                link |
                
                 or gymnastics or handstands or on your road bike.
             
            
                link |
                
                 This is unfortunately what I don't want to name brands,
             
            
                link |
                
                 but stationary bikes where they give you
             
            
                link |
                
                 the visual experience of moving through space,
             
            
                link |
                
                 but you're not actually moving through physical space.
             
            
                link |
                
                 There's no vestibular feedback, it's all visual, right?
             
            
                link |
                
                 You're stationary on the bike, right?
             
            
                link |
                
                 So unless you're hanging off the bike in your living room,
             
            
                link |
                
                 like almost to the point you're tipping the bike,
             
            
                link |
                
                 you're not getting the actual vestibular motor
             
            
            
                link |
                
                 That mismatch is the signal that deploys
             
            
                link |
                
                 dopamine epinephrine and these other things.
             
            
                link |
                
                 I don't care how excited or how much fun the ride was
             
            
                link |
                
                 or how much music you're playing that you love,
             
            
                link |
                
                 it's not the same situation as being
             
            
                link |
                
                 out of your normal relationship to the gravitational pull.
             
            
                link |
                
                 So the first gate is to arrive at learning
             
            
                link |
                
                 at the appropriate level of autonomic arousal.
             
            
                link |
                
                 Clear and focused is best,
             
            
                link |
                
                 but don't obsess over being right there.
             
            
                link |
                
                 It's okay to be a little anxious or a little bit tired.
             
            
                link |
                
                 Then you want to make errors.
             
            
                link |
                
                 We talked about that.
             
            
                link |
                
                 And this vestibular motor sensory relationship
             
            
                link |
                
                 is absolutely key if you want to get heightened
             
            
                link |
                
                 or accelerated plasticity.
             
            
                link |
                
                 And we talked about another feature,
             
            
                link |
                
                 which is setting a contingency.
             
            
                link |
                
                 If there's a reason, an important reason for you
             
            
                link |
                
                 to actually learn, even if you're making failures,
             
            
                link |
                
                 the learning will be accelerated.
             
            
                link |
                
                 So there's really four things
             
            
                link |
                
                 that you really need to do for plasticity as an adult.
             
            
                link |
                
                 And I would say that these also apply to young people.
             
            
                link |
                
                 And there's an interesting
             
            
                link |
                
                 kind of a thought experiment there as well,
             
            
                link |
                
                 which is if you look at children,
             
            
                link |
                
                 they are moving a lot in different dimensions.
             
            
                link |
                
                 They are sometimes hanging from trees
             
            
                link |
                
                 or I was a kind of a,
             
            
                link |
                
                 my sports were always things
             
            
                link |
                
                 where I tended to get hurt a lot, fall a lot.
             
            
                link |
                
                 So there's a skateboarding for me when I was younger.
             
            
                link |
                
                 So a lot of falling and rolling
             
            
                link |
                
                 and various things of that sort,
             
            
                link |
                
                 but whatever sport the kids are playing,
             
            
                link |
                
                 or even if they don't play a sport,
             
            
                link |
                
                 they tend to move in a lot of different relationships
             
            
                link |
                
                 to gravity, more dimensionality to their movements,
             
            
                link |
                
                 I should say, than adults.
             
            
                link |
                
                 And one of the questions that's always kind of been
             
            
                link |
                
                 in the back of my mind is,
             
            
                link |
                
                 as we age, we get less good at engaging in neuroplasticity.
             
            
                link |
                
                 Part of that is because as the brain ages,
             
            
                link |
                
                 there are certain changes to the way
             
            
                link |
                
                 that neurons are structured,
             
            
                link |
                
                 their molecular components, et cetera,
             
            
                link |
                
                 but it's kind of a self-amplifying,
             
            
                link |
                
                 or I should say, a self-degenerating,
             
            
                link |
                
                 self-degenerating cycle where as we get older,
             
            
                link |
                
                 we tend to get more linear and more regular
             
            
                link |
                
                 about the specific kinds of movement.
             
            
                link |
                
                 So we get on the treadmill or we take the walk,
             
            
                link |
                
                 or we just always go up the same stairs, et cetera,
             
            
                link |
                
                 and there's less opportunity typically
             
            
                link |
                
                 for engaging these relationships
             
            
                link |
                
                 to the gravitational pull
             
            
                link |
                
                 through the vestibular motor sensory convergence
             
            
                link |
                
                 that we talked about a moment ago.
             
            
                link |
                
                 And so you sort of have to wonder
             
            
                link |
                
                 whether or not the lack of plasticity
             
            
                link |
                
                 or the reduced plasticity in older individuals,
             
            
                link |
                
                 which includes me, would reflect the fact
             
            
                link |
                
                 that those chemicals aren't being deployed
             
            
                link |
                
                 because we're not engaging in certain behaviors,
             
            
                link |
                
                 as opposed to we can't engage in the behaviors
             
            
                link |
                
                 because the chemicals aren't being deployed.
             
            
                link |
                
                 Now, I have a feeling it's both.
             
            
                link |
                
                 These have a reciprocal relationship.
             
            
                link |
                
                 And I certainly, again, I don't think it would be wise
             
            
                link |
                
                 for anyone who doesn't have the muscle stabilizing skills
             
            
                link |
                
                 or the bone density, et cetera,
             
            
                link |
                
                 to start doing inversions and things of that sort.
             
            
                link |
                
                 That's not what I'm talking about here.
             
            
                link |
                
                 But it's interesting to think about
             
            
                link |
                
                 the sorts of exercise that we engage in.
             
            
                link |
                
                 We all know that getting the heart rate elevated
             
            
                link |
                
                 three to five times a week is really good for us,
             
            
                link |
                
                 for cardiovascular health.
             
            
                link |
                
                 I think there's a ton of data to support that now.
             
            
                link |
                
                 Some load-bearing exercise is important
             
            
                link |
                
                 for increasing bone density
             
            
                link |
                
                 and maintaining muscular strength
             
            
                link |
                
                 and proprioceptive feedback,
             
            
                link |
                
                 because I'm sure many of you know this,
             
            
                link |
                
                 but resistance exercise actually trains
             
            
                link |
                
                 the nerve to muscle connections
             
            
                link |
                
                 as much as it does the muscles themselves,
             
            
                link |
                
                 something I talked about at the beginning of the episode.
             
            
                link |
                
                 But I think most of us could stand to increase the degree
             
            
                link |
                
                 to which we engage this vestibular system in novel ways.
             
            
                link |
                
                 And that can be done quite safely
             
            
                link |
                
                 through a number of different mechanisms.
             
            
            
                link |
                
                 but people who do that sort of thing
             
            
                link |
                
                 are very familiar with orienting their body differently
             
            
                link |
                
                 according to the gravitational pull.
             
            
                link |
                
                 They're lying down, then they're standing up,
             
            
                link |
                
                 then they're turning, they're leaning their head.
             
            
                link |
                
                 So again, it's this pitch, yaw, roll thing.
             
            
                link |
                
                 And again, if you're very skilled at surfing,
             
            
                link |
                
                 you're actually not going to open up plasticity
             
            
            
                link |
                
                 It's in the learning of these new relationships to gravity
             
            
                link |
                
                 that the windows for plasticity are enhanced.
             
            
                link |
                
                 So I want to make sure that I underscore the fact
             
            
                link |
                
                 that this vestibular thing that I've been describing
             
            
                link |
                
                 is a way to really accentuate plasticity.
             
            
                link |
                
                 It's tapping into an inborn biological mechanism
             
            
                link |
                
                 where the cerebellum has outputs
             
            
                link |
                
                 to these deep brain nuclei
             
            
                link |
                
                 associated with dopamine, acetylcholine, and norepinephrine.
             
            
                link |
                
                 You don't want to endanger yourself
             
            
                link |
                
                 in the course of pursuing these activities,
             
            
                link |
                
                 but it is a powerful mechanism.
             
            
                link |
                
                 That's kind of an amplifier on plasticity,
             
            
                link |
                
                 as is high contingency.
             
            
                link |
                
                 If you really need to learn conversational French
             
            
                link |
                
                 to save your relationship,
             
            
                link |
                
                 the chances are you're going to learn it.
             
            
                link |
                
                 There are limits, of course,
             
            
                link |
                
                 to the extent to which one can accentuate
             
            
                link |
                
                 or accelerate plasticity.
             
            
                link |
                
                 You know, the ceiling on this is not infinite.
             
            
                link |
                
                 Although we don't know how high it goes,
             
            
                link |
                
                 I think it's reasonable to say
             
            
                link |
                
                 that if someone put a gun to my head and said,
             
            
                link |
                
                 learn conversational French in the next 120 seconds,
             
            
                link |
                
                 that conversational French would be limited
             
            
                link |
                
                 probably to just one word,
             
            
                link |
                
                 probably the word we or something like that,
             
            
                link |
                
                 because I can't stuff in all the knowledge all at once.
             
            
                link |
                
                 I mean, I think that's the dream of brain machine interface
             
            
                link |
                
                 that one will be able to download a chip
             
            
                link |
                
                 into their hippocampus or cortex
             
            
                link |
                
                 or some other brain structure
             
            
                link |
                
                 that would allow them to download conversational French.
             
            
                link |
                
                 And someday we may get to that
             
            
                link |
                
                 as that capability may come about.
             
            
                link |
                
                 Right now, it does not exist,
             
            
                link |
                
                 nor is there a specific pill or chemical
             
            
                link |
                
                 that will allow you to download more information
             
            
            
                link |
                
                 This is the issue around nootropics
             
            
                link |
                
                 I've talked about before.
             
            
                link |
                
                 There are things that can increase focus,
             
            
                link |
                
                 mainly things that increase acetylcholine
             
            
                link |
                
                 and transmission through the nicotine system,
             
            
                link |
                
                 things that can increase dopamine, things like L-tyrosine.
             
            
                link |
                
                 Again, I'm not recommending these.
             
            
                link |
                
                 You need to heed the warnings on those bottles,
             
            
                link |
                
                 but they will increase these neurochemicals.
             
            
                link |
                
                 And there are, of course,
             
            
                link |
                
                 things that will increase epinephrine,
             
            
                link |
                
                 things like caffeine or some people,
             
            
                link |
                
                 because of prescription, take Adderall.
             
            
                link |
                
                 I'm, again, not suggesting people take any of these things.
             
            
                link |
                
                 In fact, today I focused almost exclusively
             
            
                link |
                
                 on behavioral tools and ways of structuring learning bouts
             
            
                link |
                
                 that will allow you to access more plasticity
             
            
                link |
                
                 regardless of age.
             
            
                link |
                
                 And they center around things that I'm sure
             
            
                link |
                
                 if you look around you, you'll see evidence for,
             
            
                link |
                
                 oh, incremental learning is powerful,
             
            
                link |
                
                 or, oh, the vestibular system
             
            
                link |
                
                 can open up opportunities for plasticity.
             
            
                link |
                
                 I'm sure that the yogis out there are all saying,
             
            
                link |
                
                 wait, this sounds exactly like yoga.
             
            
                link |
                
                 We're supposed to push to an edge and do these inversions
             
            
                link |
                
                 and do all those sorts of things.
             
            
                link |
                
                 Well, I want to be clear.
             
            
                link |
                
                 I never said anyone should do inversions.
             
            
                link |
                
                 I said that the vestibular system is a valuable portal
             
            
                link |
                
                 into some of these neurochemical states
             
            
                link |
                
                 that favor plasticity.
             
            
                link |
                
                 But not so seldom I hear from the yoga community,
             
            
                link |
                
                 and they will say things like,
             
            
                link |
                
                 much of what you're saying about how the brain works
             
            
                link |
                
                 or neuroplasticity has already been described
             
            
                link |
                
                 is embedded in yoga practices.
             
            
                link |
                
                 And I just want to be very clear.
             
            
                link |
                
                 I have tremendous respect for the yoga community
             
            
                link |
                
                 and the practices.
             
            
                link |
                
                 I've done yoga from time to time.
             
            
                link |
                
                 I find it challenging and valuable.
             
            
                link |
                
                 I'm not a regular practitioner.
             
            
                link |
                
                 But the problem with yoga
             
            
                link |
                
                 is exactly the same problem with science,
             
            
                link |
                
                 which is that yoga has a lot of practices
             
            
                link |
                
                 for which there are very specific names,
             
            
                link |
                
                 but no description or lending of understanding
             
            
            
                link |
                
                 And science has a lot of mechanisms
             
            
                link |
                
                 and a lot of publications and papers
             
            
                link |
                
                 for which there's very little, if not no description
             
            
                link |
                
                 of tools and practices.
             
            
                link |
                
                 So my goal in not just today,
             
            
                link |
                
                 but in many ways throughout the course of the podcast
             
            
                link |
                
                 is to bridge the gaps between these various disciplines
             
            
                link |
                
                 in ways that are grounded mainly
             
            
                link |
                
                 to the fields of neuroscience and some related fields.
             
            
                link |
                
                 So yes, it's true that I look at things
             
            
                link |
                
                 mainly through the lens of science,
             
            
                link |
                
                 but that's not to say
             
            
                link |
                
                 that it exhaustively explains everything about anything,
             
            
                link |
                
                 nor is it to say that it's the only lens
             
            
                link |
                
                 through which one could look at
             
            
                link |
                
                 something like neuroplasticity.
             
            
                link |
                
                 So I just want to acknowledge that I have great respect
             
            
                link |
                
                 for all these different practices and communities.
             
            
                link |
                
                 And I think that indeed,
             
            
                link |
                
                 there are many cases in which
             
            
                link |
                
                 different communities and practices
             
            
                link |
                
                 have been aimed at targeting the same goals or outcomes.
             
            
                link |
                
                 Science and neuroscience
             
            
                link |
                
                 through an understanding of mechanism
             
            
                link |
                
                 can allow all of us
             
            
                link |
                
                 to gain a kind of common understanding
             
            
                link |
                
                 about what those practices are
             
            
                link |
                
                 and how to access things like neuroplasticity,
             
            
            
                link |
                
                 And I do believe, as I've said previously on this podcast,
             
            
                link |
                
                 that understanding mechanism
             
            
                link |
                
                 affords us a certain flexibility,
             
            
                link |
                
                 and I don't mean physical flexibility.
             
            
                link |
                
                 I mean a flexibility
             
            
                link |
                
                 when we can't engage in a particular behavior,
             
            
                link |
                
                 maybe we're injured
             
            
                link |
                
                 or maybe we're not in the right situation
             
            
                link |
                
                 to do a particular practice,
             
            
                link |
                
                 but by thinking about mechanism,
             
            
                link |
                
                 we can adapt our circumstances.
             
            
                link |
                
                 I've talked about this with sleep.
             
            
                link |
                
                 If you're rigidly attached to one protocol
             
            
                link |
                
                 of always looking at sunlight
             
            
                link |
                
                 at one particular time in the morning and in the evening,
             
            
                link |
                
                 that is not as valuable as understanding the mechanisms
             
            
                link |
                
                 of why you might look at sunlight
             
            
                link |
                
                 at one particular time versus another,
             
            
                link |
                
                 because that affords you a flexibility,
             
            
                link |
                
                 allows you to adapt,
             
            
                link |
                
                 and life is very dynamic,
             
            
                link |
                
                 and we don't have control
             
            
                link |
                
                 over all the external conditions all the time.
             
            
                link |
                
                 And so understanding mechanism
             
            
                link |
                
                 through the lens of neuroscience,
             
            
                link |
                
                 I do believe can be very powerful
             
            
                link |
                
                 because of course there are multiple ways to access dopamine.
             
            
                link |
                
                 There are multiple ways to adjust limbic friction.
             
            
                link |
                
                 It's not just through respiration.
             
            
                link |
                
                 Of course, there are many ways to do that.
             
            
                link |
                
                 And so my overall goal here in this episode
             
            
                link |
                
                 and with this podcast
             
            
                link |
                
                 is to give you some understanding of the mechanisms
             
            
                link |
                
                 and the insights into the underlying biology
             
            
                link |
                
                 that allow you to tailor
             
            
                link |
                
                 what these kind of foundational mechanisms are
             
            
                link |
                
                 to suit your particular learning needs.
             
            
                link |
                
                 So I really thank you for your time and attention today.
             
            
                link |
                
                 I've covered a lot of material.
             
            
                link |
                
                 I very much encourage questions in the comment section
             
            
                link |
                
                 if you're looking at this on YouTube,
             
            
                link |
                
                 and if you're not and you're listening to it
             
            
                link |
                
                 on Apple or Spotify,
             
            
                link |
                
                 please feel free to visit us over on the YouTube channel
             
            
                link |
                
                 and put your questions in the comment section.
             
            
            
                link |
                
                 This entire month is all about neuroplasticity.
             
            
                link |
                
                 There's a lot to cover,
             
            
                link |
                
                 but I'm very excited to delve deeper into this topic
             
            
                link |
                
                 as it relates to your particular interests.
             
            
                link |
                
                 Many of you have graciously asked
             
            
                link |
                
                 how you can help support the podcast.
             
            
                link |
                
                 The best way you can do that
             
            
                link |
                
                 is to subscribe to the YouTube channel
             
            
                link |
                
                 if you haven't done that already,
             
            
                link |
                
                 as well as to place questions in the comment section below
             
            
                link |
                
                 or comments if you'd like to give us feedback.
             
            
                link |
                
                 Also to subscribe on Apple and or Spotify,
             
            
                link |
                
                 and Apple allows you to leave a five-star review
             
            
                link |
                
                 if you believe we deserve a five-star review,
             
            
                link |
                
                 as well as leave comments about the podcast.
             
            
                link |
                
                 In addition, if you can suggest the podcast
             
            
                link |
                
                 to your friends, to your family members,
             
            
                link |
                
                 or anyone that you think might be able to use
             
            
                link |
                
                 and appreciate the information,
             
            
                link |
                
                 that's a terrific way to support us.
             
            
                link |
                
                 And of course, check out our sponsors
             
            
                link |
                
                 that we mentioned at the beginning.
             
            
                link |
                
                 That's a terrific way to support us as well.
             
            
                link |
                
                 Several times throughout today's episode,
             
            
                link |
                
                 as well as on previous episodes of the podcast,
             
            
                link |
                
                 I've talked about various supplements
             
            
                link |
                
                 that can be useful for enhancing sleep,
             
            
                link |
                
                 enhancing neuroplasticity, et cetera.
             
            
                link |
                
                 And again, I want to emphasize that I always think
             
            
                link |
                
                 that behavioral practices are the place to start.
             
            
                link |
                
                 I don't think supplements should ever be
             
            
                link |
                
                 the first line of entry for people looking
             
            
                link |
                
                 to enhance these aspects of their nervous system in life.
             
            
                link |
                
                 But for those of you that are interested in supplements
             
            
                link |
                
                 and the supplements that I take,
             
            
                link |
                
                 I'm pleased to announce that we partnered with Thorne,
             
            
                link |
                
                 T-H-O-R-N-E, and Thorne makes supplements
             
            
                link |
                
                 that are, in my opinion, of the very highest stringency
             
            
                link |
                
                 in terms of what's listed on the bottle
             
            
                link |
                
                 is actually what you'll find in the bottle.
             
            
                link |
                
                 This is a serious issue for the supplement industry,
             
            
                link |
                
                 as well as just the overall quality
             
            
                link |
                
                 of the materials they put into their supplements.
             
            
                link |
                
                 If you'd like to take a look at the supplements
             
            
                link |
                
                 that I take, as well as explore any of them for yourself,
             
            
                link |
                
                 you can go to Thorne.com slash U slash Huberman.
             
            
                link |
                
                 And if you look there, you'll see a number
             
            
                link |
                
                 of the different supplements that I take.
             
            
                link |
                
                 And if you decide to purchase any of them,
             
            
                link |
                
                 you'll get 20% off your order.
             
            
                link |
                
                 So that's Thorne, T-H-O-R-N-E slash U slash Huberman
             
            
                link |
                
                 to see the supplements that I take
             
            
                link |
                
                 and to explore if any of them are right for you.
             
            
                link |
                
                 In the next episode of this podcast,
             
            
                link |
                
                 we're going to continue to explore neuroplasticity.
             
            
                link |
                
                 This, as you may recall, is the way that we go about things
             
            
                link |
                
                 here at the Huberman Lab Podcast,
             
            
                link |
                
                 which is to really drill deeply into a topic
             
            
                link |
                
                 for three or four or even five episodes
             
            
                link |
                
                 so that by the end of those episodes,
             
            
                link |
                
                 all of you have a very firm understanding
             
            
                link |
                
                 of how to apply the principles of neurobiology
             
            
                link |
                
                 to the specific practices and endeavors
             
            
                link |
                
                 that are most important to you.
             
            
                link |
                
                 So I very much thank you for your time and attention.
             
            
                link |
                
                 I know it's a lot of information
             
            
                link |
                
                 and it takes a bit of focus and attention
             
            
                link |
                
                 and certainly will trigger plasticity
             
            
                link |
                
                 to learn all this information.
             
            
                link |
                
                 I want to encourage you and just remind you
             
            
                link |
                
                 that you don't have to grasp it all at once,
             
            
                link |
                
                 that it is here archived.
             
            
                link |
                
                 And then if you want to return to the information,
             
            
                link |
                
                 it will still be here.
             
            
                link |
                
                 And that I most of all really appreciate
             
            
                link |
                
                 your interest in science.
             
            
                link |
                
                 Thank you so much.